- Adenocarcinoma is the most common lung cancer which
usually arises from peripheral small bronchi and is often
associated with a scar. The tumor cells form glands and
secrete mucin. Mucus stains bright pink with mucicarmine
stain and PAS after diastase
- Bronchioloalveolar carcinoma (BAC) classically spreads in a
single layer on top of alveolar septa that serve as scaffolding
for the malignant cell growth. In half the tumors the cells
are tall, well-differentiated, mucin-producing with basally
located nuclei. Nonmucinous BAC is composed of tall
columnar cells or cuboidal cells growing along the alveolar
walls
- SCC, most strongly associated with smoking, can be well,
moderately or poorly differentiated. The tumor cells are
large, with pink cytoplasm and keratinization, forming
keratin pearls. In the poorly differentiated carcinomas, the
cells are highly atypical with rare individual cell
keratinization
- Small cell carcinoma, regardless of histologic subtype, lacks a
defined architectural pattern. It is composed of sheets of
haphazardly arranged small cells with scantly cytoplasm. At
low power, the tumor appears blue due to the closely opposed
nuclei. There are numerous mitotic figures and foci of
necrosis are present
Gross
Mass near hilum
Lymph nodes
Squamous cell ca
Adeno Ca infiltrating around cartilage
Broncho-alveolar ca gross
Broncho-alveolar ca
Broncho-alveolar ca gross
Broncho-alveolar ca gross
Broncho-alveolar ca
?
SCC
SCC
SCC