Correct Answer = A.
Inhaled ipatropium bromide, taken on a regular rather than PRN basis, should form the cornerstone of therapy for patients with COPD. If monotherapy fails, patients should then be tried on inhaled B-agonists. Theophylline should be reserved for patients who remain moderately symptomatic despite combined ipatropium and B- agonist use. Oral steroids should be added only as a last resort and continued, even as an inhaler, only if objective evidence of benefit associated with their use can be demonstrated.