Clinical presentations of  S. aureus  infection.

• Impetigo
• Deep infections: (Abscess,  Osteomyelitis , Cellulitis, Lung abscess etc) 
• Toxic shock syndrome
• Acute infective endocarditis

Both Staphylococcus aureus and Streptococcus pyogenes (group A strep) have many enzymes which act as virulence factors allowing these bacteria to invade tissue from patients with normal immunity and spread from infection at a local site to the bloodstream.