Pathology

P ulmonary

Aliya N. Husain, M.D.

Gross photograph of normal lungs and heart. The pleural surface is smooth and shiny. The lungs extend down to the apex of the heart.

Cut surface of normal lung.

Cut surface of normal lung (same as in fig. 2).

Right main bronchus is longer and more in line with the trachea (gross photograph, posterior view).

Microscopic section of normal bronchus showing respiratory epithelium, submucosal glands and cartilage.

High power of fig. 6, with pseodostratified respiratory epithelium at top and cartilage at bottom.

Microscopic section of normal lung showing terminal bronchiole, respiratory bronchiole, alveolar duct, alveolar sac, and alveoli.

High power of normal alveoli.

Electron micrograph of type II pneumocyte with nucleus in upper right corner and lamellar body (surfactant) in middle.

Red, consolidated and hypocrepitant lungs in hyaline membrane disease (HMD) (gross picture).

Low power photomicrographic of HMD showing immature lung with hyaline membranes.

High power showing eosinophilic (pink) acellular hyaline membrane lining air spaces.

Gross photograph of bronchopulmonary dysplasia (BPD). There is irregular scarring with depressed and hyperinflated areas.

Low power of lung with BPD; severe fibrosis at upper left, compensatory emphysema of less damaged area at bottom right.

Post-surfactant BPD with less fibrosis and arrest in lung development resulting in fewer though larger alveoli.

X-ray of patient with left-congenital diaphragmatic hernia (CDH), after barium meal.

Severe pulmonary hypoplasia, more marked on left, in patient with left CDH. As compared to the heart, the lungs are extremely small.

Gross photograph of congenital cystic adenomatoid malformation (CCAM) type I. There is one large predominating cyst filled with mucin.

Microscopic picture showing respiratory type epithelium living cyst in CCAM, type I.

CCAM, type II, intrapperative picture showing multiple cyst.

CCAM, type II, cut surface of lung showing multiple small cysts.

Microscopic picture of CCAM, type II, with cysts lived by ciliated epithelium.

High power of fig. 23, showing living epithelium of cyst in CCAM, type II.

Low power photomicrograph of adult respiratory distress syndrome (ARDS) showing hyaline membranes and interstitial edema.

High power of fig. 25, acute ARDS.

Cut surface of normal lung, though edemetous for comparison with fig. 28.

Idiopathic pulmonary fibrosis, cut surface of lung with fibrosis and antheacosis.