Listeria monocytogene

Listeria monocytogenes is a zoonoses. Carried by some animals.

In many foods (cabbage, milk products, soft cheese, pasteurized milk, sliced dale meats and cheese). Mexican style soft cheese has been implicated in a large out break of listeriosis.

Can  grow at refrigerator temperatures. 

Susceptible hosts Access to humans

Exposure to contaminated food.

Transplacental infection (mother to infant)

Human defences

Suppression of cell mediated immunity due to cyclosporine, azathioprine and prednisone. Azathioprine, cyclosporine and glucocorticoids suppress the ability of macrophages to ingest and kill intracellular pathogens in this patient.

Listeria is able to manipulate host cell action (actin) to propel it into pseudopods that extend to adjacent host cells. Thus, listeria can spread from cell to cell with minimal contact with the host immune system. 

Clinical diseases

Causes bacteremia and meningitis.


Other useful evaluations

Therapeutic strategy Prevention

Only by not being exposed to contaminated food?

Other clinical infections with these organisms