CHOLANGIOLES: Called also bile ductules and ducts of Hering are situated at the periphery of the portal space.
PORTAL LYMPHATICS: Invisible,are around vessels and bile ducts.They drain lymph from the Disse spaces to the hilus of the liver connecting with lymphtics from the glissonian capsule.
INFLAMMATORY CELLS: Presence of lymphocytes and macrophages is normal.Presence of polymorphs, eosinophils and plasma cells is abnormal.
CONNECTIVE TISSUE: Consists of interlacing type I collagen fibers.There is elastic tissue which increases with age.
PERIPORTAL LIMTING PLATE:It is a row of small hepatocytes immediately around the portal connective tissue.
SPACE OF MALL: Space between limiting plate and portal field.It contains villi .
NERVES: Sympathetic from coeliac ganglion and
parasympathetic from vagus.They regulate metabolism
and vascular and ductal motility.Adrenergic,cholinergic
and peptidergic fibers penetrate the lobules where VIP,
glucagone,substance P and calcitonin are identified.
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