Learning Goal and Enabling Objectives
- After completing the assigned reading and attending the lecture related to this
topic, you will be able to describe the characteristics of acid-fast bacteria, especially
Mycobacterium tuberculosis and the diseases (tuberculosis) they cause.
To achieve the goal of this lecture, you will be able to:
- Name the causative agents for tuberculosis, non-tuberculous mycobacterial
infections, and leprosy.
- Define "acid fastness" and describe the principle of acid fast
- Describe the characteristics of acid fast bacteria, especially Mycobacterium
tuberculosis and pathogenic factors contributing to the virulence of this organism.
- Describe how tuberculosis is transmitted.
- Describe the process of infection leading to active primary and secondary
- Explain why activated macrophages and the normal cellular immune system are
important in the resistance of hosts to tuberculosis.
- Explain how tuberculosis is diagnosed.
- Describe the principle underlying the tuberculin test and how the results of the
test should be interpreted in normal and AIDS patients.
- Explain why tuberculosis and nontuberculous mycobacterial infections have become
a serious problem among AIDS patients.
- Differentiate M. tuberculosis from agents responsible for non-tuberculous
- What are the characteristics of M. leprae?
References: Sherris Medical Microbiology, Chapter 27 Last Updated: December 10, 1996 Created: March 14, 1996