Loyola University Medical Education Network

Stratum granulosum

Loyola University Medical Center

The progressive maturation of a keratinocyte is charcterized by the accumulation of keratin, called keratinization. The cells of the stratum granulosum (SGR) accumlate dense basophilic keratohyalin granules (seen on the close-up view). These granules contain lipids, which along with the desmosomal connections, help to form a waterproof barrier that functions to prevent fluid loss from the body.

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Jason R. Swanson
Last Updated: November 15,1996
Created: January 19, 1996