Microbiology & Immunology:  Medical Education Pages.

REVIEW OF MEDICAL MICROBIOLOGY

MEDICAL MYCOLOGY


Dr Tadayo Hashimoto M.D.
Professor
Department of Microbiology & Immunology

10. Conditions often underlying opportunistic fungal infections include all of the following EXCEPT:

  1. use of broad-spectrum antibacterial antibiotics for extended periods
  2. therapeutic use of immunosuppressive drugs
  3. therapeutic use of radiation
  4. loss of T-helper-cell functions due to human immunodeficiency virus infections
  5. all of the above

(E) All of the conditions listed in the question predispose individuals to opportunistic mycotic infections. Candidiasis, cryptococcosis, and aspergillosis are common fungal infections associated with acquired immunodeficiency syndrome. Prolonged use of broadspectrum antibiotics may alter the normal microbial flora promoting the growth of opportunistic pathogens. Radiation damages or kills various types of cells that are essential for normal immune response. (Joklik et al, p. 1136; Ryan et al, pp. 815-820)

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