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Current Clinical Trials

 

 

Bladder Cancer

University of Southern California - Multicenter Trial of Adjuvant Chemotherapy in Organ-Confined Bladder Cancer Based on p53 Status

Patients undergoing cystectomy for bladder cancer are serum tested for abnormalities in the p53 gene. Patients demonstrating abnormal p53 genes are randomized to either chemotherapy or observation following cystectomy. Patients with normal p53 genes are observed. Recurrence and survival of the three groups is compared.

For more information contact:

 

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Ilex/NCI - Phase III Randomized, Double-Blind Study of DFMO versus Placebo in Low Grade Superficial Bladder Cancer

Patients with either newly diagnosed or recurrent bladder cancer will be randomized to either DFMO or placebo following resection of the tumor.

For more information contact:

 

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Endourology

Prospective Randomized Trial of Shockwave Lithotripsy and Percutaneous Nephrolithotomy for Lower Pole Nephrolithiasis (Lower Pole Study 2)

This study is designed to evaluate different treatments for stones located in the lower part of the kidney. There are currently many ways (or procedures) that are used to treat kidney stones in this location. One procedure is called shock wave Lithotripsy (SWL), and the other procedure is called percutaneous nephrolithotomy (PCNL). This study will attempt to determine the effectiveness, the rate of complications, and the cost associated with these two forms of treatment.

Males and females over the age of 18 are eligible for this study. Females cannot enroll in this study if they are pregnant.

For more information contact:

Betty Vlamakis
(708) 216-8152
vvlamak@luc.edu

 

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Female Pelvic Medicine

-Acupuncture:

  • For Treatment of Urinary Incontinence

  • For Treatment of Nighttime Voiding

  • For Painful Bladder Syndromes

  • For Postoperative Voiding Problems

  • For Urinary Retention

Qualified women will be treated with standard acupuncture at no charge. The treatment efficacy will be studied using questionnaires.

For more information contact:

MaryPat FitzGerald, M.D., Principal Investigator
(708) 216-2180

-Incontinence Medication: Duloxetine

Qualified women will be given the study medication and undergo intensive urodynamic evaluation at no cost.

For more information contact:

Kathy Jesse, R.N., Study Nurse
(708) 216-2180

-Urinary Questionnaires

Qualified women will respond to a series of urinary incontinence questionnaires designed to understand changes in quality of life.

For more information contact:

Kathy Jesse, R.N., Study Nurse
(708) 216-2180

-Colpopexy and Urinary Reduction Testing (CURE)

Women who will have surgery for pelvic organ prolapse will follow certain testing prior to and after their procedure. This study is funded by the National Institutes of Health - (NICHD).

For more information contact:

Kathy Jesse, R.N., Study Nurse
(708) 216-2180

-The Urinary Incontinence Treatment Network (UITN)

This NIH-sponsored clinical trial compared two common types of incontinence surgery. Qualified women will be enrolled to study their surgical outcomes in detail.

For more information contact:

Kathy Jesse, R.N., Study Nurse
(708) 216-2180

-The Obstetrical Recall Project

Women who have delivered a baby at Loyola will be asked to questions relating to their prior delivery. No testing will be done.

For more information contact:

Eman ElKadry, M.D., Study Physician
(708) 216-2180

-Voiding Habits in Normal Women (Part Two)

Following a successful study of normal women in the summer of 2001, we will be enrolling women to repeat the trial to determine the reproducibility of the data.

For more information contact:

MaryPat FitzGerald, M.D., Study Physician
(708) 216-2180

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SWOG 9346 - Intermittent Androgen Deprivation in Patients with Stage D2 Prostate Cancer, Phase III

Patients with metastatic prostate cancer are randomized to receive either continuous or intermittent (cycled) hormone therapy until disease progression.

For more information contact:

Katy Bortel 708/327-3640

Emotional Expression and Coping with Cancer: An Intervention for Patients and Their Partners

The study will assess the effects of psychological intervention on moods and symptoms in prostate cancer patients and their partners.

For more information contact:

 

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