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Clinical Faculty: Marcus L. Quek, M.D.
Clinical Instructor of Urology

Subspecialty/Clinical Expertise: Urologic Oncology

Available to See Patients at:  Cardinal Bernardin Cancer Center (Building 13 on the LUMC campus map)

Education/Training

Undergraduate: Stanford University (Stanford, California)
                           B.A. with Departmental Honors, Psychology, June 1993
                           B.S., Biological Sciences, June 1993

Medical School: University of Southern California (Los Angeles, California) M.D. with Highest Distinction, May 1997

Residency:

  • LAC + University of Southern California Medical Center
    General Surgery, July 1998-June 1999

  • LAC+ University of Southern California Medical Center
    Urology, July 1999- June 2003

Fellowship:

  • University of Southern California/Norris Comprehensive Cancer Center
    Urologic Oncology, July 2003-June 2005

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Professional Organizations:

  • Society of Urologic Oncology
  • American Urological Association
  • Endourological Society
  • American Medical Association
  • Phi Delta Epsilon Medical Fraternity, 1994
  • Psi Chi National Honor Society in Psychology, 1993
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Awards/Distinctions:

  • National Cancer Institute Fellow Travel Award for the SUO/NCI Annual Winter Meeting, December 2004
  • Aventis/SWOG Urologic Oncology Fellowship, 2003-2004
  • Praecis Pharmaceuticals/ AUA Gerald P. Murphy Scholar in Urology, April 2003
  • Recipient of The Pfizer Scholars in Urology Award, May 2002
  • Second Prize, Resident Essay Contest, Los Angeles Urological Society, "Long-Term Urodynamics Follow-Up in Bladder Augmentation for Neurogenic Bladder, " June 2002
  • Resident Teaching Award, USC Department of Urology, June 2000
  • Alpha Omega Alpha Honor Medical Society, USC School of Medicine, 1997
  • Dean's Scholar, USC School of Medicine, May 1997
  • Top 10% of graduating medical school class, USC School of Medicine, May 1997.
  • Stanford University Scholar-Athlete List, Stanford University, 1989-1990
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Publications/Presentations

Selected Articles:

ORIGINAL PEER-REVIEWED:

  1. Quek, M. L., Stein, J. P., Daneshmand, S., Miranda, G., Thangathurai, D., Roffey, P., Skinner, E. C., Lieskovsky, G., and Skinner, D. G.:  A critical analysis of perioperative mortality from radical cystectomy.  J Urol [in press] 2006.
  2. Quek, M. L., Stein, J. P., Nichols, P. W., Cai, J., Miranda, G., Groshen, S., Daneshmand, S., Skinner, E. C., and Skinner, D. G.:  Prognostic significance of lymphovascular invasion in bladder cancer treated with radical cystectomy.  J Urol 174: 103-106, 2005.
  3. Quek, M. L., Nichols, P. W., Yamzon, J., Daneshmand, S., Miranda, G., Cai, J., Groshen, S., Stein, J. P., and Skinner, D. G.:  Radical cystectomy for primary neuroendocrine tumors of the bladder:  the USC experience.  J Urol 174: 93-96, 2005.
  4. Barry, P., Chan, K. G., Hsu, J., and Quek, M. L.:  Adenomatoid tumor of the tunica albuginea invading the testes.  Int J Urol 12: 516-518, 2005.
  5. Quek, M. L., Barry, P., Stein, J. P., Lieskovsky, G., and Ginsberg, D. A.:  Combined radical retropubic prostatectomy and bladder augmentation for concomitant prostate cancer and detrusor instability.  Urology 65: 964-967, 2005.
  6. Quek, M. L., Soni, R. A., Hsu, J., and Skinner, D. G.:  Renal epithelioid angiomyolipoma associated with hyperprolactinemia.  Urology 65: 797, 2005.
  7. Daneshmand, S., Dorff, T. B., Quek, M. L., Cai, J., Pike, M. C., Nichols, P. W., and Pinski, J.:  Ethnic differences in neuroendocrine cell expression in normal human prostatic tissue.  Urology 65: 1008-1012, 2005.
  8. Daneshmand, S., Quek, M. L., Stein, J. P., Lieskovsky, G., Cai, J., Pinski, J., Skinner, E. C., and Skinner, D. G.:  Prognosis of patients with lymph node positive prostate cancer following radical prostatectomy—long term results.  J Urol 172: 2252-2255, 2004.
  9. Quek, M. L. and Daneshmand, S.:  Urology Photo Quiz:  Adrenal myelolipoma.  Resident & Staff Physician 50(7): 19-20, 2004.
  10. Stein, J. P., Dunn, M. D., Quek, M. L., Miranda, G., and Skinner, D. G.:  The orthotopic T-pouch ileal neobladder:  experience in 209 patients.  J Urol 172: 584-587, 2004.
  11. Wilson, S., Quek, M. L., and Ginsberg, D. A.:  Transurethral injection therapy for urinary incontinence after orthotopic neobladder reconstruction in women.  J Urol 172: 244-246, 2004.
  12. Quek, M. L., Ginsberg, D. A., Wilson, S., Skinner, E. C., Stein, J. P., and Skinner, D. G.:  Pubovaginal slings for stress urinary incontinence following radical cystectomy and orthotopic neobladder reconstruction in women.  J Urol 172: 219-221, 2004.
  13. Daneshmand, S., Stein, J. P., Lesser, T., Quek, M. L., Nichols, P. W., Miranda, G., Cai, J., Groshen, S., Skinner, E. C., and Skinner, D. G.:  Prognosis of seminal vesicle involvement by transitional cell carcinoma of the bladder.  J Urol 172: 81-84, 2004.
  14. Quek, M. L., Stein, J. P., Clark, P. E., Daneshmand, S., Miranda, G., Cai, J., Groshen, S., Cote, R. J., Lieskovsky, G., Quinn, D. I., and Skinner, D. G.:  Microscopic and gross extravesical extension in pathologic staging of bladder cancer.  J Urol 171: 640-645, 2004.
  15. Quek, M. L., Stein, J. P., Clark, P. E., Daneshmand, S., Miranda, G., Cai, J., Groshen, S., Lieskovsky, G., Quinn, D. I., Raghavan, D., and Skinner, D. G.:  The natural history of surgically treated bladder cancer with extravesical tumor extension. Cancer, 98:  955-961, 2003.
  16. Daneshmand, S., Quek, M. L., and Huffman, J. L.:  Endoscopic management of upper urinary tract transitional cell carcinoma—long-term experience.  Cancer, 98:  55-60, 2003.
  17. Quek, M. L., Shpall, A. I., and Daneshmand, S.:  Colourachal fistula in an adult presenting with feculent umbilical drainage.  J Urol 170:  184, 2003.
  18. Quek, M. L. and Ginsberg, D. A.:  Long-term urodynamics followup of bladder augmentation for neurogenic bladder.  J Urol 169: 195, 2003.
  19. Quek, M. L. and Dunn, M. D.:  Knot formation at the mid portion of an indwelling ureteral stent.  J Urol 168: 1497, 2002.
  20. Hashemi, M., Peters J. H., DeMeester T. R., Huprich J. E., Quek, M., Hagan, J. A., Crookes, P. F., Theisen, J., DeMeester, S. R., Sillin, L. F., and Bremner, C. G.:  Laparoscopic repair of large type III hiatal hernia:  objective followup reveals high recurrence rate.  J Am Coll Surg 190: 553-561, 2000.

 

REVIEW ARTICLES AND NON-PEER-REVIEWED:

  1. Quek, M. L., Simma-Chiang, V., Stein, J. P., Pinski, J., Quinn, D. I., and Skinner, D. G.:  Postchemotherapy residual masses in advanced seminoma:  a review of current management and outcomes.  Exp Rev Anticancer Ther [in press] 2005.
  2. Daneshmand, S., Quek, M. L., and Pinski, J.:  Neuroendocrine differentiation in prostate cancer.  Cancer Ther 3: 383-396, 2005.
  3. Quek, M. L. and Penson, D. F.:  Quality of life in patients with localized prostate cancer.  Urol Oncol 23: 208-215, 2005.
  4. Buscarini, M., Quek, M. L., Gill, P., Xia, G., Quinn, D. I., and Stein, J. P.:  Molecular prognostic factors in bladder cancer.  BJU Int 95: 739-742, 2005.
  5. Quek, M. L., Sanderson, K., Daneshmand, S., and Stein, J. P.:  The importance of an extended lymphadenectomy in the management of high-grade invasive bladder cancer.  Exp Rev Anticancer Ther 4: 1007-1016, 2004.
  6. Quek, M. L., Sanderson, K., Daneshmand, S., and Stein, J.P.:  New molecular markers for the detection of bladder cancer.  Curr Opin Urol 14: 259-264, 2004.
  7. Quek, M. L., Stein, J. P., and Skinner, D. G.:  Current strategies for managing locally advanced bladder cancer.  Contemp Urol 16: 44-55, 2004.
  8. Quek, M. L., Stein, J. P., and Skinner, D. G.:  Is distinction between microscopic (pT3a) and gross (pT3b) extravesical extension necessary in pathologic staging of bladder cancer.  AUA News 8: 16-18, 2003.
  9. Quek, M. L., Quinn, D. I., Daneshmand, S., and Stein, J. P.:  Molecular prognostication in bladder cancer—a current perspective.  European Journal of Cancer 39: 1501-1510, 2003.
  10. Bochner, B. H., Quek, M. L., and Skinner, D. G.:  Surgical approaches to challenging retroperitoneal disease.  Contemp Urol 15: 43-56, 2003.
  11. Featured article:  Revised bladder tumor staging not clinically useful. In: Urology Times 30(12): 10-11, December 2002.
  12. Quek, M. L., Stein, J. P., and Skinner, D. G.:  Surgical approaches to venous tumor thrombus.  Sem Urol Onc 19: 88-97, 2001.

 

BOOK CHAPTERS:

  1. Quek, M. L. and Penson, D. F.:  Quality of life instruments for prostate cancer.  In: Partin, A. W. (ed) Prostate Cancer, 2005 [in press].
  2. Quek, M. L. and Skinner, D. G.:  Renal cell carcinoma.  In:  Khatri, V. P.  (ed) Clinical Scenarios of Surgical Oncology, Lippincott Williams & Wilkins, 2005 [in press].
  3. Quek, M. L. and Skinner, D. G.:  Bladder cancer presenting as hematuria.  In:  Khatri, V. P.  (ed) Clinical Scenarios of Surgical Oncology, Lippincott Williams & Wilkins, 2005 [in press].
  4. Quek, M. L. and Stein, J. P.:  Urinary diversions.  In:  Nachtsheim, D. A.  (ed) Urological Oncology, Landes Bioscience, Chapter 7, pp 68-80, 2005.
  5. Quek, M. L. and Stein, J. P.:  Suprapubic urinary tube placement.  In: Shoemaker, W. C., Velmahos, G. C., and Demetriades, D. (eds) Procedures and Monitoring for the Critically Ill, W. B. Saunders, Chapter 19, pp139-146, 2002.
  6. Stein, J. P., Quek, M. L., and Skinner, D. G.:  Contemporary surgical techniques for continent urinary diversion:  continence and potency preservation.  In Libertino, J. A. and Zinman, L. N. (eds) Atlas of the Urologic Clinics of North America, W. B. Saunders, 9: 147-174, 2001.
  7. Quek, M. L. and Stein, J. P.:  Malignant tumors of the urogenital tract.  In Rakel, R. E. and Bope, E. T. (eds) Conn’s Current Therapy, 2001, W. B. Saunders, pp 748-757, 2001.

INVITED EDITORIAL COMMENTS AND LETTERS:

  1. Quek, M. L., Stein, J. P., and Skinner, D. G.:  Editorial Comment on:  Henry, N. L., MacVicar, G., and Hussain, M.:  Management of disease for patients with muscle-invasive and metastatic bladder cancer.  ONCOLOGY [in press], 2005.
  2. Quek, M. L. and Stein, J. P.:  Editorial Comment on:  Pruthi, R. S., Chun, J., and Richman, M.:  Reducing time to oral diet and hospital discharge in patients undergoing radical cystectomy using a peri-operative care plan.  Urology 62:661-666, 2003.

 

MANUSCRIPTS IN PREPARATION/ SUBMITTED:

  1. Daneshmand, S., Quek, M. L., Lin, E., Cote, R. J., Hawes, D., Cai, J., Groshen, S., Lieskovsky, G., Skinner, D. G., Lee, A. S., and Pinski, J.:  Glucose regulated protein GRP78 is upregulated in prostate cancer.  (Submitted to Clin Cancer Res), 2005.
  2. Pinski, J., Wang, Q., Quek, M. L., Cole, A., Danenberg, P., Danenberg, K., and Cooc, J.:  Chemotherapy induces neuroendocrine differentiation of cancer cells.  (Submitted to Nature Medicine), 2005.
  3. Youssefzadeh, D., Quek, M. L., Daneshmand, S., and Stein, J. P.:  Emphysematous pyelonephritis combined with xanthogranulomatous pyelonephritis:  a case report and review of the literature.  (Submitted to Int J Urol), 2005.
  4. Quek, M. L., Daneshmand, S., Rodrigo, S., Cai, J., Dorff, T. B., Groshen, S., Skinner, D. G., Lieskovsky, G., and Pinski, J.:  Prognostic significance of neuroendocrine expression in lymph node positive prostate cancer.  (Submitted to Urology), 2005.
  5. Stein, J. P., Quek, M. L., and Skinner, D. G.:  Lymphadenectomy in high-grade invasive bladder cancer I:  historical perspectives and rationale.  (Submitted to BJU Int), 2005.
  6. Stein, J. P., Quek, M. L., and Skinner, D. G.:  Lymphadenectomy in high-grade invasive bladder cancer II:  technical aspects and prognostic factors.  (Submitted to BJU Int), 2005.

 

ABSTRACTS & PRESENTATIONS:

  1. Nunoo-Mensah, J. W., Kaiser, A. M., Saedi, H., Essani, R., Wasserberg, N., Artinyan, A., Quek, M., Boyd, S. D., Stein J. P., Skinner, D. G., and Beart, R. W. Jr.:  Malignancy-associated-rectourinary fistulae: how often is permanent fecal or urinary diversion really necessary?  ACS Annual Clinical Congress, San Francisco, October 2005 (to be presented by Dr. Nunoo-Mensah).
  2. Quek, M. L., Daneshmand, S., Rodrigo, S., Cai, J., Dorff, T. B., Groshen, S., Lee, C., and Pinski, J.:  Prognostic significance of neuroendocrine expression in lymph node positive prostate cancer.  North Central Section AUA Annual Meeting, Chicago, September 2005.
  3. Quek, M. L., Stein, J. P., Daneshmand, S., Miranda, G., Lieskovsky, G., and Skinner, D. G.:  A critical analysis of perioperative mortality from radical cystectomy. Western Section AUA Annual Meeting, Vancouver, August 2005 (presented by Dr. Daneshmand).
  4. Pinski, J., Wang, Q., Quek, M. L., and Cole, A.:  Chemotherapy induces neuroendocrine differentiation in prostate cancer cells.  Western Section AUA Annual Meeting, Vancouver, August 2005 (presented by Dr. Pinski).
  5. Quek, M. L., Daneshmand, S., Rodrigo, S., Cai, J., Dorff, T. B., Groshen, S., Lee, C., and Pinski, J.:  Prognostic significance of neuroendocrine expression in lymph node positive prostate cancer.  Western Section AUA Annual Meeting, Vancouver, August 2005 (presented by Dr. Daneshmand).
  6. Quek, M. L., Daneshmand, S., Rodrigo, S., Cai, J., Dorff, T. B., Groshen, S., Lee, C., and Pinski, J.:  Prognostic significance of neuroendocrine expression in lymph node positive prostate cancer.  ASCO Annual Meeting, Orlando, May 2005 (presented by Dr. Dorff).
  7. Quek, M. L., Stein, J. P., Nichols, P. W., Cai, J., Miranda, G., Groshen, S., Daneshmand, S., Skinner, E. C., and Skinner, D. G.:  Prognostic significance of lymphovascular invasion in bladder cancer treated with radical cystectomy.  SUO/NCI Winter Meeting, Bethesda, December 2004.
  8. Quek, M. L., Barry, P., Stein, J. P., Lieskovsky, G., and Ginsberg, D. A.:  Combined radical retropubic prostatectomy and bladder augmentation for concomitant prostate cancer and detrusor instability.  Western Section AUA Annual Meeting, San Diego, August 2004.
  9. Yamzon, J., Quek, M. L., Daneshmand, S., Miranda, G., Cai, J., Skinner, E. C., Stein, J. P., and Skinner, D. G.:  Radical cystectomy for small cell carcinoma of the bladder:  the USC experience.  Western Section AUA Annual Meeting, San Diego, August 2004.
  10. Quek, M. L., Daneshmand, S., Katz, M., Cai, J., Stein, J. P., Skinner, E. C., and Skinner, D. G.:  Lymph node involvement in clinically localized and locally advanced renal cell carcinoma.  Western Section AUA Annual Meeting, San Diego, August 2004.
  11. Quek, M. L., Daneshmand, S., Skinner, E. C., Vaishnav, A., Cai, J., Stein, J. P., Skinner, D. G., and Lieskovsky, G.:  Biochemical and clinical outcomes after radical prostatectomy for clinically localized prostate cancer during the prostate specific antigen era.  Western Section AUA Annual Meeting, San Diego, August 2004.
  12. Schuckman, A. K., Barry, P., and Quek, M. L.:  Penoscrotal elephantiasis:  a BIG problem.  Western Section AUA Annual Meeting, San Diego, August 2004 (presentation to be made by Dr. Schuckman).
  13. Daneshmand, S., Tabibian, L., Quek, M., Best, C., Ortega, A., Nonoo-Mensah, J., and Skinner, D. G.:  The York-Mason repair for recto-vesical fistula.  Western Section AUA Annual Meeting, San Diego, August 2004 (presentation to be made by Dr. Daneshmand).
  14. Daneshmand, S., Tyler, S., Quek, M. L., Stein, J. P., Cai, J., Skinner, E. C., and Skinner, D. G.:  Pathologic factors associated with positive lymph nodes in renal cell carcinoma.  Western Section AUA Annual Meeting, San Diego, August 2004 (presentation to be made by Dr. Daneshmand).
  15. Daneshmand, S., Quek, M., Youssefzadeh, D., and Dunn, M. D.:  Multicystic mesothelioma as a consequence of augmentation enterocystoplasty.  Western Section AUA Annual Meeting, San Diego, August 2004 (presentation to be made by Dr. Daneshmand).
  16. Youssefzadeh, D., Quek, M. L., Daneshmand, S., and Stein, J. P.:  Emphysematous pyelonephritis combined with xanthogranulomatous pyelonephritis.  Western Section AUA Annual Meeting, San Diego, August 2004 (presentation to be made by Dr. Youssefzadeh).
  17. Daneshmand, S., Dorff, T. B., Quek, M., Cai, J., Nichols, P. W., Pinski, J.:  Ethnic differences in neuroendocrine cell expression in normal human prostatic tissue.  Western Section AUA Annual Meeting, San Diego, August 2004 (presentation to be made by Dr. Daneshmand).
  18. Daneshmand, S., Lin, E., Dorff, T.B., Quek, M., Cai, J., Lee, A. S., Pinski, J.:  Glucose regulated protein GRP-78 is upregulated in prostate cancer.  Western Section AUA Annual Meeting, San Diego, August 2004 (presentation to be made by Dr. Daneshmand).
  19. Stein, J. P., Dunn, M. D., Quek, M. L., Miranda, G., and Skinner, D. G.:  The orthotopic T-pouch ileal neobladder:  experience in 209 patients.  AUA Annual Meeting, San Francisco, May 2004 (presented by Dr. Stein).
  20. Daneshmand, S., Tyler, S., Quek, M. L., Stein, J. P., Cai, J., Skinner, E. C., and Skinner, D. G.:  Pathologic factors associated with positive lymph nodes in renal cell carcinoma.  AUA Annual Meeting, San Francisco, May 2004 (presented by Dr. Daneshmand).
  21. Quek, M. L., Daneshmand, S., Skinner, E. C., Vaishnav, A., Cai, J., Stein, J. P., Skinner, D. G., and Lieskovsky, G.:  Biochemical and clinical outcomes after radical prostatectomy for clinically localized prostate cancer during the prostate specific antigen era.  AUA Annual Meeting, San Francisco, May 2004.
  22. Quek, M. L., Buscarini, M., and Dunn, M. D.:  Laparoscopic excision of a pelvic kidney in an adult.  Western Section AUA Annual Meeting, Lake Las Vegas, November 2003.
  23. Quek, M. L., Buscarini, M., and Dunn, M. D.:  Laparoscopic excision of a pelvic kidney in an adult.  World Congress on Endourology, Montreal, September 2003 (presented by Dr. Buscarini).
  24. Daneshmand, S., Stein, J. P., Lieskovsky, G., Quek, M. L., Cai, J., Groshen, S., Skinner, E. C., and Skinner, D. G.:  Prognosis of patients with stage D1 prostate cancer following radical prostatectomy.  AUA Annual Meeting, Chicago, April 2003 (presented by Dr. Daneshmand).
  25. Quek, M. L. and Dunn, M. D.:  A knot in the middle of an indwelling ureteral stent:  a case report. Western Section AUA Annual Meeting, Kauai, October 2002.
  26. Quek, M. L., Wilson, S., and Ginsberg, D. A.:  Pubovaginal sling for the treatment of urinary incontinence after radical cystectomy and orthotopic neobladder reconstruction in women.   Western Section AUA Annual Meeting, Kauai, October 2002.
  27. Wilson, S., Quek, M. L., and Ginsberg, D. A.:  Transurethral injection therapy for urinary incontinence after radical cystectomy and orthotopic neobladder reconstruction in women.  Western Section AUA Annual Meeting, Kauai, October 2002 (presented by Dr. Wilson).
  28. Quek, M. L., Stein J. P., Miranda, G., Groshen, S., and Skinner, D. G.:  Distinction between microscopic (pT3a) and gross (pT3b) extravesical extension is unnecessary in pathologic staging of bladder cancer.  AUA Annual Meeting, Orlando, May 2002.
  29. Quek, M. L. and Ginsberg, D. A.:  Long-term urodynamics follow-up in bladder augmentation for neurogenic bladder.  AUA Annual Meeting, Orlando, May 2002.
  30. Quek, M. L. and Ginsberg, D. A.:  Long-term urodynamics follow-up in bladder augmentation for neurogenic bladder.  Annual Meeting of the Society for Urodynamics and Female Urology, Orlando, May 2002.
  31. Ginsberg, D. A. and Quek, M.:  Long-term urodynamics follow-up in bladder augmentation.  Western Section AUA Annual Meeting, Anchorage, September 2001.

 

SENIOR HONORS THESIS:

  1. Quek, M. L.:  Distinguishing between visual and conceptual priming:  identical pictures, different exemplars, and words as priming stimuli in a picture-naming task.  Psychology Department, Stanford University (Advisor:  John D. E. Gabrieli, PhD), 1993.

 

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Selected Presentations/Lectures/Abstracts:

“Prostate Cancer Management—Long-Term Outcomes and Future Directions: The USC Experience” –Urology Grand Rounds, University of Rochester, October 6, 2004

 “Radical Cystectomy and Urinary Diversion” – Lecture for Operating Room Staff, LAC+USC Medical Center.  May 21, 2004.

“Radical Retropubic Prostatectomy” – Lecture for New Operating Room Nurse Program, LAC+USC Medical Center.  March 5, 2004.

 “Urinary Diversion: Principles and Practice” – Monthly lecture for medical students on Urology Clerkship, LAC+USC Medical Center, 2003-2004.

 

 

 

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Selected Research Initiatives:

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More information on Dr. Quek

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