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Newsletter
- Winter 2007
Welcome to the Department of Surgery Newsletter. We hope you find this information helpful.
From Where l Sit............
Richard L. Gamelli, MD, FACS
With
the death of Dr. Robert J. Freeark on December 13, 2006, our department and
medical center has not only lost a long-time member of our faculty but one of
the pillars of our success. Bob was known for many great accomplishments during
his tenure as chair of the Department of Surgery which spanned 25 years. He
took our department from a fledgling department with no recognition and a
medical center that was not sure of the direction it needed to proceed and built
one of the premier clinical departments in the nation. Bob’s department became
recognized for its clinical excellence and the many talented members of his
department who played leadership roles in American surgery such as William
Baker, Jack Pickleman, Herbert Greenlee, Frank Folk, Robert Mason, Ray Warpeha,
Fred Littooy and Frank Harford to name a few. The Surgical Residency under Dr.
Freeark flourished and trained nearly 200 chief residents during his tenure.
My introduction to Bob Freeark occurred during the fall of
1989
when I was asked to come to Loyola. Bob had a vision of building a research
institute in alignment with a clinical program. The notion of translational
research had not yet become common in any ones’ mind but that’s exactly what Bob
had in his own mind. He had spent a sabbatical year visiting premier trauma and
burn centers and had come up with the concept that patient care could only be
improved by linking what happen at the bedside to the laboratory and finding
ways to improve patient care. Bob’s commitment and support of the building of
our Burn and Shock Trauma Institute during its early and fragile formative years
was critical to the successes we enjoy today.
Having the opportunity to follow in Bob’s footsteps as
chair, now for eleven years, has convinced me more than ever of his wisdom,
judgment and fairness.
Bob was passionate about Chicago and the Chicago Bears
and, on most days, the Cubs. He was always focused on Loyola and what it needed to
do next if it was to continue be a successful academic medical center. His
vision for Loyola went beyond that of the Department of Surgery. Over the years,
Bob’s key investments were in people. His support was not only philosophically
and emotionally but financially as he often helped those outside of the
department because it was the right thing to do. Researchers in basic science or
a graduating resident wanting to do a fellowship could count on Bob for his
support of their career.
Bob always gave the best to his patients and was totally
dedicated to their care as well as to the training and education of students and
residents. He continued to amaze me when I would walk into our conference room
and see the chalk talk that Bob had just given our students on gastric
physiology. What was diagramed on the board was well beyond what any senior
resident and many of the junior faculty likely knew.
I could not have had the opportunity to follow in the
footsteps of a greater chair than Bob Freeark. His support throughout my tenure
was one of encouragement and compliment. Bob’s advice was always well reasoned,
balanced and added another level of clarity to the decision that needed to be
made.
If the success of a man is gauged by the successes he
allows others to achieve, Bob Freeark’s career is one of spectacular success.
Medical students, surgical residents, fellows, practicing surgeons, and their
patients continue to benefit today. They will do so for decades to come because of
his leadership and commitment to excellence.
Feature
Articles
Midwest Surgical Association Meeting
The Grand Hotel on Mackinac Island, Michigan served as the
location for the 49th Annual meeting of the Midwest Surgical Association from
August 6 – 9, 2006. Numerous faculty members and residents from
the Department
of Surgery attended the meeting and presented their research work and discussed
the scientific presentations of their colleagues. The meeting represented an
outstanding blend of stimulating scientific presentations and an enjoyable
social program that involved members and their families. There's nothing quite
like a dinner in the dining room of the Grand Hotel. The
last night of the meeting we dined on the porch at Fort Mackinac, which,
overlooks the
Straits of Mackinac, the Mackinac Bridge, and Mackinac City. The view of
the moon rising was spectacular. As you can see,
our department was well represented by many members and their
families at this meeting.
Holiday Brunch
On Sunday, December 3, The Department of Surgery hosted their annual holiday
party. This year’s event, unlike those in previous years,
was a family
affair. Department faculty and staff had the opportunity to invite their
spouses or significant others and, new this year, their children and
grandchildren. Not only were partygoers’ taste buds treated to a host of
magnificent and seemingly endless culinary
delights, there was also an array of
entertainment options.
Activities that charmed and thrilled the young and young
at-heart included a face-painter, magician, balloonist, and storyteller. The
freshly fallen snow on the landscape of The Edgewood Valley Country Club
provided the perfect setting for this most enjoyable occasion.
Surgical Resident
Recognition Wall
The Department of Surgery has realized a long-standing goal
to give special recognition to our surgical resid ents who have graduated and
gone on to make their mark in the world. On December first, the “Surgical
Residents Through The Years” wall was established in the department.
The wall is located in the hallway adjacent to the reception area. The
cherry wood and corian scrolls that comprise this wall are engraved with the
names of surgical residents starting with the year 1970 and going through our
past graduating year, June 2006. At the completion of each academic year,
the names of the graduating residents will be added to the wall. This wall
is truly an impressive tribute to those that have graduated from our surgical
residency program.
Department of Surgery Annual Cocktail Reception
The Department of Surgery hosted its Annual Cocktail
Reception on Tuesday, October 10. The event was held at the Chicago
Cultural Center in the Yates Gallery. The
Gallery overlooked
Chicago’s Millennium Park, and the view was absolutely spectacular.
Attendees
were entertained by the sounds of the Stu Hirsh Trio and treated to a variety of
food stations and dessert tables. With the American College of Surgeons 92nd.
Annual
Clinical Congress being held in Chicago, the event was attended by many
of our alumni and former faculty. If comments that our Administrative team
received are any indicator, the evening was a major success. You may want to
take a moment to check out the photos from the evening to see if you recognize
anyone.
Clinical
Spotlight
Faculty Member Passionate About Trauma Surgery
Thomas J. Esposito, M.D., M.P.H., a Loyola trauma and
critical care surgeon since 1991, wears
many hats, but you might not expect the
ones he wears in his free time: chef and Santa. Esposito has been called “a
culinary artist of Italian dishes” and enjoys making pizza in a wood-burning
oven in his basement bistro.
As for Saint Nick, Esposito explained “for two years running, now, I’ve played
Santa in a PetSmart store, helping raise money for a dog rescue group my wife is
involved with.”
If animal rescue is a passion of Julie, his wife of four years, trauma surgery
is his passion.
“It’s more than a job…. It’s an adventure,” said Esposito, professor of surgery
at the Stritch School of Medicine and chief of the trauma section in the
Department of Surgery. “It’s challenging and diverse. You get to do it all.” 
Calling himself “part policy advocate, part educator, part
clinician and part researcher,” Esposito is also director of the Injury Analysis
and Prevention Programs for the Burn and Shock Trauma Institute of Loyola
University. Additionally, he travels the country as a speaker, trauma center
reviewer and consultant to government and private injury related agencies, law
firms and trauma systems.
The nationally and internationally recognized trauma
expert’s diverse interests fall into three main areas: injury control, trauma
systems and acute care surgery.
Injury control
“Injury is probably the biggest problem facing this
nation,” Esposito said. “It’s the leading cause of death and disability for
those below the age of 44 in this country and … is responsible for the greatest
proportion of all U.S. health care expenditures.”
One major hurdle to reducing injuries is that injury generally is not viewed as
a disease that can be prevented. All injuries are controllable, according to
Esposito, who does not use the word accident.
“We need to use the same types of strategies for reducing injuries that were
used for [encouraging] smoking cessation,” he said.
Esposito believes in a Public Health model of injury control based on an
approach that involves all of the following strategies:
-
Engineering: technical improvements, such as safety belts,
air bags and smoke detectors
-
Economic incentives and disincentives, for example,
insurance premium discounts for drivers with no car crashes
-
Enforcement and enactment of laws aimed at reducing
injuries
-
Education
Although Esposito educates about injury prevention in grade
schools and elsewhere, he calls education the least effective method because
many people, especially young people, disregard safety warnings and advice. He
also works closely with the National Highway Traffic Safety Administration (NHTSA)
and other organizations to develop more effective injury control strategies.
Esposito laments that NHTSA will not be renewing its
support of the Loyola Prevention Program due to federal budgetary constraints.
He adds that intramural and extramural funding for the program have been
surprisingly difficult to obtain, placing the program in serious jeopardy of
extinction. “At this point, support from any source would be welcomed,” he says.
Esposito co-chairs the physician-led traffic safety
advocacy group End Needless Death on Our Roadways. The group is dedicated to
decreasing the incidence of impaired and other dangerous driving behaviors. It
advocates screening for alcohol abuse after every crash and treating substance
abusers.
Injury control is something that every physician can be
involved in, and not just by practicing safe driving themselves, he said.
Doctors can be spokespersons and champions of injury prevention and control in
their communities, hospitals, or professional organizations. They can lobby for
health policy laws, such as better reimbursement for trauma and emergency care,
funding for implementation of trauma systems, and compensation laws for victims
of violent crimes or just participate in trauma care- which many surgeons are
reluctant to do.
Trauma systems
Trauma surgeons should document their treatments and
outcomes for trauma registries, said Esposito, who is medical director of
Loyola’s trauma registry.
As one of 20 Level I trauma centers in Illinois, Loyola
University Medical Center collects and submits burn and trauma data to the
Illinois Department of Public Health. Using the data obtained from the registry,
Esposito and his co-workers conduct research and publish trauma outcomes that
assist in improving the treatment of trauma.
Loyola’s trauma center was the first in Illinois to be
verified by the American College of Surgeons (ACS), and Esposito encourages
other trauma centers to seek ACS verification and trauma systems to participate
in the ACS trauma system evaluation program. He was instrumental in facilitating
a recent independent evaluation of the Illinois state trauma system by the ACS.
Acute care surgery
Esposito is no less passionate about his clinical work.
“He has dedicated his life to excellence in patient care
and improving access to trauma care for injured patients,” said Fred A. Luchette,
M.D., director, Division of Trauma, Critical Care and Burns, and also the
Ambrose and Gladys Bowyer Professor of Surgery.
Indeed, Esposito is concerned about access for all
emergency patients. Changing trauma surgery into “acute care surgery” will, he
believes, help surgeons to better respond to the needs of patients who present
with an emergency condition.
In addition, Esposito is an outspoken advocate for the
discipline of trauma surgery at a time when fewer physicians are choosing the
subspecialty and its demanding lifestyle. He recommends broadening the trauma
surgeon’s scope of practice to elective and emergency general surgery, trauma,
and surgical critical care.
“We’re going to have to change the paradigm of practice
scope and practice lifestyle in order to attract more people into trauma
surgery,” said Esposito, who completed both clinical and research fellowships in
traumatology at the University of Maryland after his surgical residency at St.
Elizabeth’s Hospital in Boston. He obtained his MPH and injury prevention
credentials from the University of Washington.
“I’d like to see more people go into this field and lend
their talents and spirit to the cause,” he said. “I think it's one of the
noblest aspects of surgery. You are able to have an impact on society and its
major public health problem.”
Although Esposito admits, as he gets older, that when he
gets paged at 3 a.m. to consult on a “great case,” he thinks, “There are no
great cases at 3 in the morning,” but in retrospect, after a little rest,
changes his mind. “Two days later … it does somehow always end up being a great
case and a great overall career.”
Surgery In
the News
Faculty Named America's Top Doctors
Three of the Department of Surgery’s faculty rank in the
top 1 percent of America’s doctors, according to New York-based Castle Connolly
Medical Ltd.’s new book, America’s Top Doctors, ™ (sixth edition). The
following faculty received this prestigious distinction.
Dr. John J. Brems
Professor of Surgery
Division of General Surgery
Dr. Richard L. Gamelli
The Robert J. Freeark Professor
Chairman, Department of Surgery
Chief, Burn Center
Director, Burn and Shock Trauma Institute
Professor of Pediatrics
Dr. Howard P. Greisler
Professor of Surgery and Cell Biology, Neurobiology and Anatomy
Division of Peripheral Vascular Surgery
America’s Top Doctors identifies leading physicians in the
U.S. considered outstanding by their peers. Castle Connolly,
www.castleconnolly.com, a publisher of national and regional consumer healthcare
guides, surveyed tens of thousands of medical doctors in leadership positions
and in private practice. The results name 5,000 physicians in more than 60
specialties and subspecialties, treating some 1,700 medical conditions and
diseases.
Dr. Esposito interviews on local and
national radio
Thomas J. Esposito, M.D., M.P.H., was interviewed on local & national
radio and television stations in November. Dr. Esposito is the
Co-Chairperson of “End Needless Death on Our Roadways” (END), a
physician-led traffic safety advocacy group. The topic for his interviews was
“Ten States Make Deadly Fatal Fifteen List for Three Years Straight.”
This is an annual list of the 15 deadliest states in the country for impaired
driving (Illinois ranks 13th). The “Fatal Fifteen” are states in
which 41% or more of all traffic fatalities are alcohol related. Dr.
Esposito stated that, “The biggest thing is to raise people’s consciousness… as
to the preventability of a lot of these incidents.” The key is to change
people’s attitudes about driving under the influence, the same way years of
anti-smoking campaigns and taxes have turned public opinion around to
smoking. For more information on END, visit their website:
www.endneedlessdeath.org
Resident Corner
Being a Part of the Team
by Dr. Christine Gresik
I remember as a medical student here at Loyola,
receiving a lecture from Doctor Sheehan during which he said,
“The
key to being a good doctor is devoting as much time to each patient as each
patient needs.” It’s almost halfway through my internship now, and I
finally realize that this is what practicing medicine is really all about …
just not quite as literally. Let’s face it; if patients always had their
way, our morning rounds would turn into all day rounds as each
would command the constant attention of the Service to attend to his needs.
It’s now that I realize what Dr. Sheehan was implying …we, as physicians,
need to be there, not only for our patients’ medical needs, but also for the
emotional, mental and spiritual concerns that arise in anyone requiring a
surgical intervention. I now realize how lucky I am, to be a part of a
healthcare “team” as this is far too great a task for someone to accomplish
on her own. I am thankful for all the people that make my life so much
easier by being there for the patients when I am unable.
As much as I like to think that residents have the busiest
and most chaotic job in the hospital, the fact is that nurses often work just as
many hours and attend to each and every patients’ needs all day long. Having a
good relationship with the nurses ultimately grants the patient better care and
expedites the road to recovery. A positive partnership can make a call night a
completely different experience. Nurses can spare you the 0100 multivitamin
refill request or the 0400 call letting you know that your patient’s potassium
is stable, provided that you have a nice attitude, respect their role as
valuable members of the team and, of course, complete your discharge paperwork
in a timely fashion! They really are a wealth of knowledge, and I have come to
recognize the frequency by which I depend on their experience…let’s face it,
most of the nurses have been working for far longer than I.
Another member of the team that is not praised nearly
enough is the social worker. We were told the first day of internship that the
discharge plan is to start the day that our patients are admitted. For some
patients, even this does not always allow an adequate amount of time. I cannot
give our social workers enough credit for the countless number of referrals for
placement, phone calls to insurance companies, and wound vac requests that they
place on a daily basis.
Of course,
there are many more to acknowledge for whom I am equally grateful. In the
future, when I reflect upon my residency … I hope that I will remember all of
the people that touched my life during my education, and not just my attendings
or fellow residents. Rather, the nurses that fed me Thanksgiving dinner in the
Burn Unit, the respiratory therapist that showed me how to set up my first
ventilator, scrub nurses who took the time to teach me proper draping,
pharmacists that help to clarify medication requests, chaplains that spend hours
at a patient’s bedside, and on and on. Not all of the learning I will do during
residency will take place in the OR or by reading Cameron or Sabiston … I am
certain that some knowledge can only be acquired by learning from the
experiences of everyone on the “team.”
General Surgery Recruitment News
…Winter 2006-2007
To paraphrase a famous quote, “Neither snow nor rain nor
heat nor gloom of night” could stay our General Surgery applicants from
attending a recent recruitment session. Such was the case with our first
recruitment event of the year held on Friday, December 1st. Despite hundreds of
flight cancellations amidst the first snowstorm of the season, 35 tenacious
medical students made their way to the Department of Surgery to meet our program
officials, faculty and residents. Some had driven many hours, some had
rearranged last-minute flights, and even one arrived at our Friday evening
function without her luggage. Yet, the event was overwhelmingly successful. In
spite of the challenging weather, our candidates showed their true mettle and
presented themselves very positively. Our faculty and residents deserve kudos,
too, for coming out in force to show the Department of Surgery at its best.
A second recruitment day was held on Thursday, December
14th. Happily, weather conditions were more favorable and again, we hosted 35
eager young recruits. The entire Department of Surgery graciously handled the
disruption of this event amidst the normal business routine, and once again, the
feedback from our recruits was uniformly positive.
Two additional General Surgery recruitment events are
scheduled for mid-January. At the conclusion of our recruitment season, we will
have interviewed 115 of the best and brightest medical students in the country.
The faculty, residents, and staff have shone in our past events and our
Department workspace has never been more beautiful. The results of this will
become evident in July as we welcome several bright young surgeons to join our
ranks and build upon the fine tradition of training provided here at
Loyola.
General Surgery Recruitment Statistics – 12/21/06:
-
758 Applications Received in Total
-
336 Applications for Preliminary Surgery
-
654 Applications for Categorical Surgery
For Categorical Track:
-
324 US Medical Colleges (LCME) Students/Graduates
-
21 Osteopathic Students/Graduates
-
308 International Medical Students/Graduates
-
26 AOA Members (at time of Application Submission – early
Fall 2006)
-
158 Candidates Invited to Interview (Categorical)
For Preliminary Track:
-
57 US Medical Colleges (LCME) Students/Graduates
-
5 Osteopathic Students/Graduates
-
273 International Medical Students/Graduates
-
0 AOA Members (at time of Application Submission – early
Fall 2006)
-
23 Candidates Invited to Interview (Preliminary)
Accreditation News …
The Department of Surgery has undergone three site visits from the Accreditation
Council for Graduate Medical Education (ACGME) within 2006. As this is a very
long process awaiting word from the various Residency Review Committees, the
last of the accreditation decisions has just been received. The programs
reviewed this year were Plastic Surgery, Surgical Critical Care and Vascular
Surgery.
In the tradition of exemplary education at Loyola, the
three programs received an endorsement of continued full accreditation.
The tentative next site visit for each program is listed
below:
Plastic Surgery – April 1, 2010
(4 year cycle)
Surgical Critical Care – October
1, 2009 (3 year cycle)
Vascular Surgery - October 1,
2010 (4 year cycle)
The General
Surgery residency program is tentatively scheduled for their next ACGME site
visit in February of 2008.
Surgical Education Program
Announces Education Honor Roll, Mid Year 2006-2007
Residents
Drs. S. Made, R. Candage, J.
Eberhardt, M. Hulvat, M. Keldahl, K. McGill, M. Mosier, S. Obi, S. O'Donnell, S.
Sen, M. Sherrow, M. Tempel, A. Thawani.
Faculty
Drs. G. Aranha, B. Aulivola,
R.L. Gamelli, W. Gunnar, D. Holt, R. Joehl, E. Omi, R.L. Reed, J. Santaniello,
S. Sarker, V. Shayani, G. Silver, K. Yao.
Education Honor Roll was
determined by 3rd year med student evaluations from recent 2006-2007 quarters.
Criteria were the following (rating scale of 1 = poor, 5 = excellent):
residents, average rating ≥ 4.3 from ≥ 2 students; faculty, average rating ≥ 4.5
from ≥ 2 students.
Research
Leading Research Explores Novel Cell-based Anti-bacterial Therapies
Fighting the bacterial infections of critically ill
patients has become increasingly difficult in the last 30 years. While more
bacteria have become resistant to currently available antibiotics, no new class
of antibiotics has been discovered, especially those that combat multi-drug
resistant nosocomial infections.
These issues provide the impetus for the leading-edge
research of Ravi Shankar, Ph.D., Associate Professor in the Loyola University
Chicago Stritch School of Medicine Departments of Surgery and Cell Biology,
Neurobiology and Anatomy.
“One of the problems in inflammation and sepsis research,
is that we have accumulated significant knowledge but no viable treatment or
diagnostic modalities have resulted from these efforts,” said Dr. Shankar, who
received his doctorate in biochemistry at the University of Tasmania in
Australia and his post-doctoral fellowship training in vascular biology at the
Cleveland Clinic in Ohio.
“A significant part of my research focuses on how the host
responds to infection and what role does bone marrow leukocyte development play
in this host-response,” explained Dr. Shankar. “Normally, a patient with a
nosocomial infection in a hospital setting is treated for a period of time with
an antibiotic regimen. Usually, we assess the efficacy of our treatment through
broad physiological parameters such as resolution of fever, blood leukocyte
counts and overall improvements in vital signs ” he said. “But we don’t know
whether the patient is responding to a given treatment at a very early stage and
if we need to change the treatment, both of which are very important for the
care of critically injured and often immune-compromised burn and trauma
patients.”
Dr. Shankar is taking a different approach to resolve these
issues. Using animal models, he and his basic science research team in the Burn
and Shock Trauma Institute are studying whether infection-responsive cellular
parameters may provide a model for predicting the effectiveness of antibacterial
treatments.
The prerequisite for sepsis is extensive local and systemic
infection, according to Dr. Shankar. “The bacterial organisms keep quiet for a while
until they grow to sufficient numbers. Each cell produces a small molecule that
comes out of the bacterium,” explained Dr. Shankar. “When there is sufficiently
high levels, they travel back into the cell and turn on the genes that produce
the virulence of that particular organism.”
Dr. Shankar and his team are developing several bacterial
strains that lack specific virulence-associated genes and reconstituted bacteria
where the specific gene product is replaced. Using these bacterial strains, his
laboratory is attempting to understand the relationship between the cellular
responses of the host and specific gene responses of the pathogen. Dr. Shankar’s
team is developing a correlation of the host immune response and gene products
of the pathogen. Their goal is to use this cell-based information to evaluate
the effectiveness of therapies and create new and better ones.
Ravi Shankar’s research focuses on a number of areas,
including new product development. These projects are performed in partnership
with biotechnology companies, many spawned from research at the University of
Wisconsin in Madison.
The scientist is testing a type of “Star Wars” product with
a Madison-based company called ConjuGon. The antibacterial system involves the
transfer of specific “killer” genes from mutated E. coli to the pathogen
through a transfer process called conjugation.. “So when the altered donor
bacteria come into contact with a pathogenic bug in the tissue, it injects the
‘killer’ gene into it, producing proteins that are cytotoxic and kill the
pathogens,” the researcher said. Successful thus far in a mouse model, the next
phase is to test the product using a pig model, he added.
For his efforts, Dr. Shankar received the Robert A.
Lindberg Award for Basic Science Research from the American Burn Association in
2006.
Dr. Shankar is also testing a human-skin substitute that is
bioengineered to produce naturally occurring antibiotic substances to clear the
wound of bacterial infection and promote wound closure in burn patients. The
product, created by another Madison company called Stratatech, provides an
alternative for burn patients who develop wound infections with multi
drug-resistant organisms.
Dr. Shankar’s laboratory is funded by a variety of sources,
including the National Institutes of Health, United States Department of
Defense, ConjuGon Inc., and Stratatech Corporation.
As a basic scientist, Dr. Shankar derives satisfaction from
learning about the clinical challenges his physician colleagues face in caring
for the critically injured and septic patients. “I have learned so much about
clinical medicine over the years,” he said. “If I want to improve patient care
through my research, I have to know what the real clinical problems are.”
2006 Alcohol and Immunology Research Interest Group (AIRIG)
Meeting at Loyola University
Like other scientific meetings, one of the primary purposes
of holding AIRIG meetings is to provide the opportunity for investigators to
discuss current and novel research in the field. Unlike
many meetings in which
the same set of senior researchers give the majority of the oral presentations, AIRIG meetings have an additional commitment to be inclusive of more junior
scientists and those who are new to the field as speakers. To accomplish this,
for the 2006 meeting, Dr. Elizabeth Kovacs, Professor and Vice Chair of
Research, Department of Surgery, and her co-organizers, Drs. Lou Ann Brown,
Emory University, Luisa DiPietro, University of Illinois Chicago, Robert Cook,
University of Iowa, and Thomas Jerrells, University of Nebraska, chose to yield
the podium. Dr. Kovacs said, “Giving oral presentations will increase the
exposure of junior investigators to the other researchers in the field.” She
also believes that this will avail the speakers the opportunity to receive
critique from more senior scientists and may foster collaboration. The
philosophy was, and continues to be, that in order to bring more investigators
into the field, one needs to 1) provide a “user-friendly” environment for young
developing scientists and those who are new to the field and 2) invite speakers
from laboratories and institutions that have not previously participated in the
meetings.
The 2006 AIRIG meeting was held at Loyola University on
November 17, 2006. Invited
speakers included David Guidot, MD, Emory (Dampened
GM-CSF signaling and impaired innate immune function in alveolar macrophages in
the alcoholic lung), Carl Waltenbaugh, PhD, Northwestern (Rapid
appearance of IgE in a murine model of alcohol consumption), Martha Gentry-Neilsen,
PhD, Nebraska
(Effects of concurrent drinking and smoking on innate defenses
against pneumonia), Gary G. Meadows, PhD, Washington State (Effects
of chronic alcohol consumption on natural killer cell maturation and trafficking),
Michael Sander, MD, Universitaetsmedizin-Berlin Charite (Alcohol use
disorders cause immune suppression and increased infection rates in surgical
settings: preventive strategies - from bench to bedside?), and Gregory Bagby,
PhD, Louisiana State University Health Science Center New Orleans (Consequences
and mechanisms of slowed neutrophil recruitment in p ulmonary
host defense against bacterial infections after ethanol exposure). Seven additional
speakers were selected from submitted abstracts. This group had two Assistant
Professors, Drs. Kevin L. Legge, PhD (University of Iowa) and Ronda M. Brand,
PhD (Evanston Northwestern Hospital), a postdoctoral fellow, Xiaoling Li, MD,
(University of Alabama, Birmingham), two graduate students, Eva Murdoch (PhD
Student, Loyola University Medical Center) and Audrey H. Lau (MD/PhD Student,
University of Pittsburgh Medical Center), a research technician (Mike Shay from
University of Iowa), and a senior alcohol researcher scientist who had not
attended previous AIRIG meetings (Ping Zhang, MD, PhD, Louisiana State
University Health Sciences Center). Finally, Sam Zakhari, PhD, National
Institute on Alcohol Abuse and Alcoholism, NIH spoke about scientific gaps in
the NIAAA portfolio. The meeting was attended by over 65 participants and 25
posters were presented. The meeting was supported by an NIIH R13 meetings grant
given to Dr. Kovacs. The majority of the funds were earmarked for travel awards
for students, postdoctoral fellows,1/9/2007 1:26:00 PM and minority scientists.
Additional support was provided by Loyola’s Department of Surgery and Alcohol
Research Program.
Because of the overwhelming success of the meeting,
Dr.
Kovacs and her colleagues plan to host the 2007 meeting of the Alcohol and
Immunology Research Interested Group focusing at Loyola on Friday November 16,
2007. The theme of the 2007 meeting will be “Systemic
& Organ-Specific Inflammatory Responses after Alcohol Exposure.”
Confirmed invited speakers (and their tentative
titles) for the upcoming AIRIG meeting include, Gavin
Arteel, PhD (University of Louisville) Role of plasminogen activator inhibitor‑1 (PAI‑1) in
the initiation and progression of alcohol‑induced liver disease; Angela
Dolganiuc, MD (University of Massachusetts) Alcohol interferes with TLR4
signaling within raft membrane microdomains; Bin Gao, MD, PhD (National
Institute of Alcohol Abuse and Alcoholism, NIH) Effects of ethanol
consumption on innate immunity in the liver; Steve Nelson, MD (Louisiana
State University Health Science Center New Orleans) Title: TBA; Chantel
A. River, PhD (Louisiana State University Health Science Center, Shreveport)
The role of Toll‑like receptor‑4 in steatohepatitis; Geoff Thiele, PhD
(University of Nebraska Medical Center) The induction of autoimmune hepatitis
by malondialdehyde‑acetaldehdye adducts.
Publications/Presentations/Awards
Publications
Aranha, G.V., Aaron, J., and Shoup, M.C.: “Critical
Analysis of a Large Series of Pancreaticogastrostomy following
Pancreaticoduodenectomy” Arch Surg 2006; 141:574-580.
Aranha, G.V., Aaron, J.M., Shoup, M.C., and
Pickleman, J.: “Current Management of Pancreatic Fistula after
Pancreaticoduodenectomy.” Surgery 2006; 140: 561-569.
Boehmer, E.D., Meehan, M.J.,
Cutro, B.T., Gomez, C.R., and Kovacs,
E.J.: 2006. Aberrant TLR signaling in
macrophages from aged mice. (ed., JD Schwarzmeier), The 6th
International Cytokine Conferences. Bologna, Italy, Monduzzi Editor, pp
31-34.
Brewster, L.P., Bennet, B.K., and Gamelli,R.L.:
Application of Rehabilitation Ethics to a Selected Burn Patient Population’s
Perspective. J Am Coll Surg. 2006 Nov;203(5):776-771.
Brown, K., Shoup, M.C., Abodeely, A., Hodul, P.,
Brems, J.J., and Aranha, G.V.: “Central Pancreatectomy from Benign
Pancreatic Lesions.” HPB 2006; 8:142-14.
Carlson, A.P., Schermer, C.R., and Lu, S.W.:
Retrospective evaluation of anemia and transfusion in traumatic brain injury. J
Trauma 2006 Sep;61 (3):567-71.
Davis, K.A., Abodeely, A., Reed, R.L.,
Esposito, T.J., Santaniello, J.M., Poulakidas,
S., and Luchette, F.A.: Predictors of the need for nephrectomy
after renal trauma. J Trauma 2006 January; 60(1):164-170.
Davis, K.A., Esposito, T.J., Reed,
R.L., Santaniello, J.M., and Luchette, F.A.:
Nutritional gain vs. financial gain? The role of metabolic carts in the surgical
ICU. J Trauma 2006; 61:1436-1440.
Eckert, M.J., Davis, K.A., Reed, R.L., Esposito, T.J., Santaniello, J.M.,
Poulakidas, S., Gamelli, R.L., and Luchette, F.A.:
Ventilator-associated Pneumonia, like Real Estate: Location Really Matters. J
Trauma 2006 January;60 (1):104-110.
Eckert, M.J., Wade, T.E., Davis, K.A.,
Luchette,
F.A., Esposito,
T.J., Poulakidas, S., and
Gamelli, R.L.:
Ventilator-Associated Pneumonia after Combined Burn and Trauma is due to
Associated Injuries and not the Burn Wound. J Burn Care Res. 2006 July/August;
27(4): 457-462.
Emanuele, N., LaPaglia, N., Kovacs, E.J., and
Emanuele, M.A.: 2006. Effects of acute and chronic ethanol administration on
proinflammatory cytokines of the hypothalamic-pituitary-gonadal axis in male
rats. Alcohol, in press.
Esposito,
T.J.: Rank and File Weighs in on Trauma
and General Surgery Issues: Results from a Survey of ACS Fellows. Bull AM Coll
Surg. 91(9): 13-20, 2006.
Esposito,
T.J., Crandall, M.,
Reed, R.L.,
Gamelli,
R.L., and Luchette, F.A.:
Socioeconomic factors, medicolegal issues, and trauma patient transfer
trends: Is there a connection? J Trauma 2006; 61:1380-1388.
Esposito,
T.J., Leon, L., and Jurkovich, G.J.: The
Shape of Things to Come: Results From A National Survey Of Trauma Surgeons On
Issues Concerning Their Future. J Trauma 60:8-16, 2006.
Esposito, T.J., Rotondo, M.F. Barie, P.S., et al:
Making The Case For A Paradigm Shift In Trauma Surgery. J Am Coll Surg. 202:
655-667, 2006.
Fitzgerald, D.J., Radek, K.A., Chaar, M., Faunce, D.E.,
DiPietro, L.A., and Kovacs, E.J.: 2006. Acute ethanol exposure impairs
the early inflammatory response during wound healing. Alcoholism: Clin. Expt.
Res., in press.
Gomez, C.R., Boehmer, E.D., Nomellini, V., and Kovacs,
E.J.: 2006. Signal transduction in the aging innate immune system.
Current Immunology Reviews, invited review, in press.
Gomez, C.R., Hirano, S., Cutro, B.T., Birjandi, S., Baila,
H., Nomellini,V., and Kovacs, E.J.: 2006. Advanced age
exacerbates the pulmonary inflammatory response after lipopolysaccharide
exposure. Crit. Care Med., in press.
Gomez, C.R., Plackett, T.P., and Kovacs, E.J.:
2006. Aging and estrogen: Modulation of inflammatory responses after injury.
Expt. Gerontol., in press.
Gosain, A., Matthies, A.M., Dovi, J.V., Barbul, A.,
Gamelli, R.L.,
and DiPietro, L.A.: Exogenous pro-angiogenic stimuli cannot prevent
physicologic vessel regression. J Surg Res.2006 Oct;135(2):218-55.
Hurtuk, M., Reed,
R.L., Esposito, T.J.,
Davis, K.A., and
Luchette, F.A.: Trauma surgeons practice what they preach: The NTDB
story on solid organ injury management. J Trauma 2006;61:243-255.
Kapur, U., Rubinas, T., Ghai, R., Sincacore, J., Yao, K.A.,
and Rajan, P.: Prediction of nonsentinel lymph node metastases in sentinel node
positive breast carcinoma, Annals Diag Path 2006 (in press).
Keldahl, M., Sen, S., and
Gamelli, R.L.: Gastric
Rupture after Cardiopulmonary resuscitation in a burn patient. J Burn Care Res.
2006 Sept/Oct; 27(5):757-9.
Miller, C.B., Malaisrie, S.C., Patel, J., Garrity, E.,
Vigneswaran, W.T., and Gamelli,
R.L.: Intraabdominal Complications after
Lung Transplantation. J Am Coll Surg. 2006 Nov; 203(5):653-660.
Patel, J., Dutta, S., Shoup, M.C., Pickleman, J.,
and Aranha, G.V.: The impact of Clinicopathological factors on survival
of patients with Gastric Cancer. Poster Presentation. 47th Annual Meeting of
the Society for Surgery of the Alimentary Tract, Los Angeles CA, May 22, 2006.
Plackett, T.P., Colantoni, A., Heinrich, S.A., Messingham,
K.A.N., Gamelli, R.L., and Kovacs, E.J.: 2006. The early
acute phase response following burn injury in the mouse. J Burn Care Res., in
press.
Weilenberg, A., Demos, T.C.,
Luchette, F.A., and Bova,
D.: Cardiac Herniation due to Blunt Trauma: Early Diagnosis facilitated by
computed Topography. AJR Am J Roentgenol. 2006 Aug; 187(2): W239-40.
Book Chapters
Esposito, T.J.,
Luchette, F.A., and
Gamelli, R.L.: Do we Really Need Neurosurgeons in the Trauma
Center. Advances in Surgery. Cameron J (Ed) 2006, vol 40; p40; pages
213-221.
Gentillello, L., Schermer, C., and
Hungerford D.: Alcohol Interventions In Trauma Centers And Emergency
Departments: Same Place, Different Services. Alcohol And Injuries: Emergency
Department Studies In An International Perspective. World Health
Organization: Geneva, in press.
Schermer, C.R., and Genitlello, L.M.:
"Alcohol Screening and Brief Interventions in Trauma Centers" The
Alcohol Research Group.”
Editorials
Luchette, F.A.:
Editorial Commentary on “Utility of Screening for Blunt Vascular Neck Injuries
with Computed Tomographic Angiography.” J Trauma 2006; 61: 215-216.
Schermer, C.R.: Editorial Commentary on
“Effectiveness of Brief Interventions after alcohol related vehicular injury: a
randomized controlled trial.” J Trauma 2006; 61:532-533.
Presentations
Aaron, J.M., Shoup, M.C., Pickleman, J., and
Aranha, G.V.: Octreotide does not present pancreatic fistula formation
following Pancreaticoduodenectomy. Poster Presentation. Annual meeting –
American Hepato-Pancreato-Biliary Association. Miami Beach, Florida. March
9-12, 2006.
Aranha, G.V.: Quality of Life: Managing
Symptoms. Pancreatic Cancer Symposium, an event to create awareness. April 7,
2006, Northwestern Memorial Hospital. Chicago, Illinois.
Aranha, G.V.: 20th World Congress of the
International Society for Digestive Surgery. The Role of Interventional
Radiologist in the Management of Complications following Pancreaticoduodenectomy.
November 30, 2006, Rome, Italy.
Aranha, G.V.: 20th World Congress of the
International Society for Digestive Surgery. Moderator: Symposium on
Management of Pancreatic Cancer. November 30, 2006, Rome, Italy.
Aranha, G.V.: A Technique for
Pancreaticogastrostomy –Video Symposium. 20th World Congress of the
International Society for Digestive Surgery. Friday, December 1, 2006. Rome,
Italy.
Aranha, G.V.: 20th World Congress of the
Interventional Society for Digestive Surgery. Current Management of Pancreatic
Fistula following Pancreaticoduodenectomy. December 1, 2006, Rome, Italy.
Brems, J.:
Invited Discussant at the Western Surgical
Association Meeting in Los Cabos, Mexico. “Right Hepatectomy for living donor
liver donation vs. right hepatectomy for disease: intraoperative and immediate
postoperative comparison.”
Chu, H.B., Bhatti, A., Labropoulos, N., Aulivola, B.,
Hazelwood, K., Barros, M., Amaral, S., and Kalman, P.G.:
Correlation of superficial venous anatomy and reflux with clinical severity:
What have we learned through routine duplex surveillance during the endovenous
era? Midwestern Vascular Surgery Society (30th Annual Meeting, September 7-9,
2006), Cleveland, OH, Sep 7, 2006.
Esposito, T.J.:
Invited Speaker at the Annual Trauma Conference at St. Francis Medical Center
in Hartford, Connecticut. “The Dark Side of Motherhood: Domestic Violence and
Injuries to the Pregnant Woman.”
Esposito, T.J.:
Panelist on the topic of state and local response to the IOM Report on Emergency
Care in the U.S. as part of the “Future of Emergency Care Series: Regional
Dissemination Workshop” sponsored by the Institute of Medicine at Northwestern
Memorial Hospital in Chicago.
Esposito, T.J.:
Faculty Member for an international course on Quality Improvement for Trauma
Care sponsored by the Harborview Injury Prevention and Research Center at the
University of Washington in Seattle. Representatives from Ghana, Vietnam,
Brazil, Romania, Mexico participated in the course.
Gamelli, R.L.:
Invited Speaker at the 12th Annual
San Antonio Trauma Symposium. “Microbial Drug Resistance – Some New Thoughts
about an old Problem.”
Gamelli, R.L.:
Presented at the 13th Congress of the International Society for Burn
Injuries in Fortaleza-Ceara´ Brazil. “New Antibacterial Therapies through
Dynamic Pathogen Responses” and “Metabolism of Inhalation Injury.”
Gruenwald, N.D., Brems, J.J., Pierce, K., Aranha,
G.V., and Borge, M.: Excluded posterior right hepatic duct drainage after
Roux-en-Y Hepaticojejunostomy. Poster Presentation. Annual Meeting American
Hepato-Pancreato-Biliary Association, Miami Beach Florida, March 9-12, 2006.
Kalman, P.G.: Philadelphia Vascular Symposium (14th
Annual), Philadelphia, PA, Feb 24, 2006 - Feb 25, 2006. Management of carotid
aneurysms: Role of open surgical vs. endovascular repair.
Kalman, P.G.: The World Congress of the
International Union of Angiology (June 24-28, 2006), Lisbon, Portugal, Jun 25,
2006. Mesenteric occlusive disease: A rational approach in deciding the safest
intervention.
Kalman, P.G.: The World Congress of the
International Union of Angiology (June 24-28, 2006), Lisbon, Portugal, Jun 26,
2006. Moderator: Optimal management of aortic aneurysmal disease.
Kalman, P.G.: The World Congress of the
International Union of Angiology (June 24-28, 2006), Lisbon, Portugal, Jun 26,
2006. Moderator: Topical hemostatic agents: An international consensus forum.
Kalman, P.G.: The Vascular Endovascular Issues
Techniques Horizons (VEITH 2006 Symposium, sponsored by The Cleveland Clinic),
New York, NY, Nov 16, 2006. What is the best treatment for iliac occlusive
disease? Which lesion should be ballooned, which stented, which bypassed and
which left alone?
Kovacs, E.J.:
“Gender differences in response to burn injury:
mechanisms and treatment,” Symposium on Regulation of Inflammatory Responses:
Influence of Gender/Sex, Bethesda, MD, September 2006.
Kovacs, E.J.:
“Aging alters innate immune responses after injury.” Symposium on Aging and
Immune Responses, Society for Leukocyte Biology, San Antonio TX, November 2006.
Kovacs, E.J.:
Chair of Session II of the NIAID meeting on “Gender-related Inflammatory
Disorders at Regulation of Inflammatory Responses: Influence of Gender/Sex,”
Bethesda, MD, September 2006.
Kovacs, E.J.:
Co-Chair of Session 1 of the NIAAA Symposium entitled “Alcohol, Intestinal
Bacterial Growth, Intestinal Permeability to Endotoxin, Medical Consequences,
and Dietary Supplements ,” Rockville, MD, October 2006.
Kovacs, E.J.:
Chaired a Symposium on Aging and Innate Immunity at the Society for Leukocyte
Biology, San Antonio, TX, November 2006.
Kovacs, E.J.:
“Alcohol, estrogen, and inflammatory responses after
injury.” Integrative Neural Immune Program, Section on Neuroendocrine Immunology
& Behavior, NIMH/NIH, Bethesda, MD, March 2007.
Kovacs, E.J.:
Chair of the Program Committee for “Alcohol and
Shock 2007,” a Satellite Symposium at the4 Shock Society Meeting, Baltimore, MD,
June 2007.
Kovacs, E.J.:
Member of the Program Committee for the Annual
Meeting of the Research Society on Alcoholism, Chicago, IL, July 2007.
Schermer, C.R.: Speaker, Detroit Trauma Symposium
November 9, "Alcohol and Injury."
Schermer, C.R.: Speaker, Detroit Trauma Symposium
November 10, "Palliative Care after Trauma."
Schermer, C.R.: Invited teacher, Gainesville
Florida February 2007. Brief Intervention Seminar.
Schermer, C.R.: Speaker, Society of Trauma Nurses
annual meeting March 2007 "Alcohol Screening and Brief Interventions."
Sherman, K.L., Obi, S.H.,
Aranha, G.V., Yao, K.A., and Shoup, M.C.:
Heparin coated stents do not protect
cancer patients from cardiac complications following non-cardiac surgery.
Poster presentation. Annual Meeting society for surgical oncology, San Diego,
California, March 24-27, 2006.
Yao, K.A.:
Poster presentation at the Society of Surgical
Oncology in Washington, DC, March 2007. “Sentinel Lymphadenectomy in Breast
Cancer Patients Greater than 70 years old.” Dr. Melissa Hulvat, Resident, is
the first author.
Yao, K.A.:
Speaker at the “From Bench to Bedside: Update
from the San Antonio Breast Cancer Symposium,” San Antonio. “Update on Breast
Cancer Surgery.”
Yao, K.A.:
Presented "BRCA in 2006: Management", Genetic Task Force, Stritch School of
Medicine, Loyola University Medical Center.
Abstracts
Gomez, C.R., Baila, H., Morgan,
M.O., Oshima, K., Nomellini, V.,
and Kovacs, E.J.: Elevated hepatic inflammatory response in aged
mice given LPS. Annual meeting of the Society for Leukocyte Biology, San
Antonio, TX. November 2006.
Gosain, A., Muthu, K., Jones,
S.B.,
Gamelli, R.L., and DiPietro,
L.A.: Norepinephrine negatively modulates wound macrophage phagocytic function
through alpha-and beta-adrenoreceptor-dependent mechanisms. Abstract
Presentation 2006 American College of Surgeons Clinical Congress.
Hulvat, M., Yao, K.A.,
Rajan, P., Sarker, S., Norton, J., and
Aranha, G.V.: Sentinel Lymphadenectomy in
Breast Cancer Patients >70yo, Society of Surgical Oncology, Washington, DC
March 2007.
Karavitis, J., Ramirez, L.,
Messingham, K.A.N., Faunce, D.E., and Kovacs, E.J.: Role
of gonadal hormones after alcohol and burn injury. Alcohol and Immunology
Research Interest Group Meeting, Maywood, IL, November 2006.
Kovacs, E.J.:
Aging, estrogen, and macrophages mediators after injury. Symposium on Aging
Research in Immunology: the Impact of Genomics. Paris, France, September 2006.
Kovacs,
E.J.: Gender differences in response to burn injury: mechanisms and
treatment. Symposium on Regulation of Inflammatory Responses: Influence of
Gender/Sex, Bethesda, MD, September 2006.
Kovacs, E.J.,
Meehan, M.J., and Boehmer, E.D.: Aging causes defects in macrophage signaling
that are limited to TLR-mediated pathways. Joint Meeting of the International
Cytokine Society and the International Society for Interferon and Cytokine
Research, Vienna, Austria August, 2006.
Kovacs, E.J.,
Plackett, T.P., Nomellini, V., Boehmer, E.D., and Gomez, C.R.: Advanced age
alters innate immune response after injury. Annual meeting of the Society for
Leukocyte Biology, San Antonio, TX. November 2006.
Melstrom, K.A., Kuzhali, M., He, L.K., Smith, J., Szilagyi,
A., Hassett, D., Gamelli, R.L., and
Shankar, R.: OxyR gene
expression of Pseudomonas aeruginosa regulates bone marrow dendritic cell
differentiation and function after burn sepsis. Abstract Presentation 2006
American College of Surgeons Clinical Congress.
Murdoch, E.L., Karavitis, J.,
Morgan, M.I., Ramirez, L., Shankar, R., Gamelli, R.L., Faunce, D.E., and
Kovacs, E.J.: Alcohol Acute ethanol exposure and burn injury: Clinically
relevant models of Pseudomonas aeruginosa infections. Alcohol and
Immunology Research Interest Group Meeting, Maywood, IL, November 2006.
Murdoch, E.L., Karavitis, J.,
Morgan, M.I., Shankar, R., Gamelli, R.L., Faunce, D.E., and Kovacs,
E.J.: Ethanol exposure prior to burn
injury increases susceptibility to Pseudomonas aeruginosa (PA) infection.
Autumn Immunology Conference, Chicago, IL,
November 2006.
Muthu, K., Szilagyi, A., He, L.K.,
Jones, S.B., Gamelli, R.L., and
Shankar, R.: Adrenergic Stimulation Augments Innate Immunity through
MØ Bacterial Phagocytosis and Killing. Abstract presented at the 2006 Joint
Meeting of the Society for Leukocyte Biology and the International Endotoxin and
Innate Immunity Society.
Nomellini, V., Faunce, D.E.,
Gomez, C.R., and Kovacs, E.J.: Chemokine levels after burn injury in
aged mice. Autumn Immunology Conference, Chicago, IL, November 2006.
Nomellini, V., Faunce, D.E.,
and Kovacs, E.J.: Increased pulmonary inflammation in aged mice
subjected to burn injury. Annual meeting of the Society for Leukocyte Biology,
San Antonio, TX. November 2006.
Sun, W., Burns, A.L., Kovacs,
E.J. and DiPietro, L.A.: Effect of ethanol exposure on endothelial
responsiveness to VEGF. Alcohol and Immunology Research Interest Group Meeting,
Maywood, IL, November 2006.
Awards and Honors
Aranha,
G.V.: America’s Top Doctor for Cancer – Castle Connolly Guide – (2005).
Aranha, G.V.: Chicago’s Top Doctors – Castle
Connolly Guide/Chicago Magazine – (2005).
Aranha, G.V.: Attending Of The Year – Loyola
Stritch School of Medicine – Class of 2007 Teaching Award.
Brems, J.J.: America's Top Doctors for 2006 -
Castle Connolly Medical Ltd..
Gamelli, R.L.: America's Top Doctors for 2006 -
Castle Connolly Medical Ltd..
Gamelli, R.L.: Appointed Treasure for the
International Society of Burn Injuries.
Greisler, H.P.: America's Top Doctors for 2006 -
Castle Connolly Medical Ltd.
Kovacs, E.J.: Asked to join the Advisory Committee
of the Emory University NIAAA-funded Alcohol and Lung Biology Training Program,
P.I. David M. Guidot, Emory University, Atlanta, GA, 2006.
Kovacs, E.J.: Served as a member of the Special
Emphasis Panel, Inflammation and Aging, ZAG1 ZIJ-5 M1, NIH, Bethesda, MD.
Kovacs, E.J.: Invited to serve on the National
Scientific Advisory Council, American Federation for Aging Research, New York,
NY.
Santaniello, J.M.: Recently appointed
Assistant Director of the "Structure of the Human Body Course" (Gross Anatomy)
for the first year medical school class.
Grants and Funding
Kovacs, E.J.: “Alcohol and Immunology Research
Interest Group Meeting.” NIH, R13 AA016751-01 (Scientific Meetings Grant
Application) $17,750 (direct costs). Period: 07/01/06 – 06/30/07. P.I.:
Kovacs, E.J.
Yao, K.A.: Notch Signaling in Cutaneous Melanoma: A
Pilot Study, PI: Yao, K.A., Harry J. Lloyd Charitable Trust Research
Award, 5/0/05-4/30/06, $100,000.
Yao, K.A.: Characterization of Notch Signaling in
Patients at High Risk for Breast Cancer, American Cancer Society Illinois
Division, PI: Yao, K.A., 5/01/06-4/30/07, $100,000.
Yao, K.A.: Trauma List and Loyola List: A Pilot
Project to Improve "Hand off" Communications and Workflow Efficiency, Central
Surgical Association Surgical Enrichment Award, PI: Yao, K.A.,
4/01/06-4/01/07, $10,000.
Yao, K.A.: Notch Signaling in Cutaneous Melanoma
and Breast Carcinoma, Cardinal Bernardin Cancer Center Clinical Research
Development Grant, 8/01/05-8/01/06, $20, 000.
Meetings
The Department of Surgery was represented at the
American College of Surgeons’ 92nd Annual Clinical Congress held in
Chicago, October 2006 by the following faculty:
Aranha, G.V.: Invited Discussant: Movie Classics
from the Past: Pancreatic Cysts, 1953 ACS Clinical Congress, Charles B. Puestow.
Brems, J.J.:
Invited Discussant: “ Proteasome Inhibitor PS-341 Inhibits NFkB and
Ameliorates Ischemia-Reperfusion Injury in Orthotopic Liver Transplant with a
Steatotic Graft.”
Gamelli, R.L.: “After Major Injury Regulatory
T-Cells Reduce Inflammation and Mortality from a “Second Hit.””
Gamelli, R.L.: “Norepinephrine Negatively
Modulates Wound Macrophage Phagocytic Function through Alpha- and Beta-
Adrenoreceptor-Dependent Mechanisms.”
Gamelli, R.L.: “OxyR Gene Expression of
Pseudomonas Aeruginosa Regulates Bone Marrow Dendritic Cell Differentiation and
Function Following Burn Sepsis.”
Luchette, F.A.: “Open Pelvic Fractures: Need to
Divert?”
Reed, R.L.: “Is Hypothermia After Major Injury Protective or Harmful?”
Shoup, M.C.: “Palliation For Pancreatic Cancer.”
Yao, K.A.: “Sentinel Node Biopsies for Thyroid
and Other Malignancies.”
The following faculty represented the Department of
Surgery at the American Association for The Surgery of Trauma’s 65th
Meeting held in New Orleans - September 2006.
Esposito, T.J.: “An Update of Trauma Surgeon
Compensation : Survey of AAST and EAST.”
Esposito, T.J.: “Trauma Center Salaries and
Financial Reports: How do you make trauma centers financially viable?”
Esposito, T.J., and Luchette, F.A.:
“Neurosurgical Needs in The Pediatric Trauma Population.”
Esposito, T.J., Santaniello, J. M., Gamelli, R. L.,
and Luchette, F.A.: “Protein Supplementation after Injury: How Much
is Enough?”
Esposito, T.J., Santaniello, J. M., Gamelli, R. L.,
and Luchette, F.A.: “A Prospective Comparison of Routine CXR vs.
Clinical Judgment for The Determination of Adequate Central Line Placement.”
Reed, R.L., Luchette, F. A., Esposito, T.J., and
Gamelli, R. L.: “Recalibration of the abbreviated injury scale (AIS)
severity score using the national trauma data bank (NTDB) improves mortality
prediction.”
Alumni News
Accomplished Surgeon-Scientist Recalls Loyola
Residency’s “Excellent Clinical Training”
Much of what Tien C. Ko, M.D. learned as a surgical
resident at Loyola University Medical Center helped to fuel his success as a
high-achieving surgeon, teacher and researcher at the University of Texas
Medical Branch in Galveston, Texas.
Ko, who served his surgical residency at Loyola from
1986-1991, is an associate professor in the Departments of Surgery, Biochemistry
and Molecular Biology at the University of Texas Medical Branch (UTMB), where he
cares for patients and teaches. Appointed to the Chela and Jimmy Storm
Distinguished Professorship in Surgical Research, he also performs basic science
research and serves as the director of Real-Time Polymerase Chain Reaction Core
facility in the Sealy Center for Cancer Cell Biology at UTMB.
After he graduated in 1986 from the University of
California, Los Angeles, School of Medicine, Ko narrowed his choices for
residency programs to Chicago. “I interviewed at 5 or 6 programs in Chicago,” Ko
said. “My top choice was Loyola because I thought the surgery residents seemed
happiest there and received excellent training as well.”
“I was used to UCLA, which had a very large student body,”
the surgeon added. “At Loyola, the attending physicians and residents seemed to
know each other very well, more than most other places.”
Through more personalized attention and dedication to
teaching, Loyola attending physicians imparted a strong tradition of clinical
excellence, Ko explained. “The attending physicians were great role models. They
challenged you to make decisions. Their standards for clinical practice were
very high,” he said.
“By the end of the residency, I was very well trained
clinically. I also developed strong judgment skills,” noted Ko. “In many
residencies, the attending physicians will tell residents what to do. At Loyola,
we were given opportunities to make decisions.” He also benefited from a wide
variety of cases and health-care settings by rotating through Loyola and other
hospitals in the Chicago area and Louisville, Kentucky.
Through mentorship with key Loyola physicians during his
residency, Ko narrowed his career to academic medicine with a focus on
gastroenterological surgery and related basic science research. In particular,
he has investigated how proteins affect cell development and their impact on
diseases of the gut, such as colon and liver cancer.
Since his residency, Ko has pursued research that has
resulted in hard-to-get National Institutes of Health (NIH) grants, either as an
individual or as part of the large research team at UTMB. Currently, he is
principal investigator on an NIH-funded project studying growth regulation in
surgical diseases of the gut. Ko also is participating in 2 multi-year NIH
training grants, as well as NIH studies exploring gastrointestinal
endocrinology. From 1994 through 1999, Ko received the National Cancer
Institute’s Clinical Investigator Award.
To date, the busy surgeon-scientist has authored or
co-authored 50 articles in peer-reviewed journals, 7 reviews and chapters, and
42 abstracts. In addition, Ko has given more than 70 oral presentations and
invited talks, and has made more than 40 poster presentations. In 2001, Dr. Ko
was elected President of the Association for Academic Surgery.
Ko also is dedicated to educating future physicians. He has
participated in the surgical clinical rotation for UTMB medical students in
their third-year clerkship and fourth-year elective. Ko also teaches the courses
“GI Hormones and the Coordination of Nutrition” and “Abdominal Workshop” to
second-year medical students.
In working with UTMB surgery residents, Ko remembers what
was most useful to him during his time at Loyola. While he enjoys teaching, the
surgeon also acknowledges its challenges. “I try to encourage residents to think
for themselves. Rather than just memorizing facts, I push them to think
critically, to make good judgments,” Ko said.
“I encourage them to be detectives and to use the physical
exam to get clues from their patients,” the surgeon noted. “No matter how long
you have been practicing medicine, you can always improve upon those skills.”
On a personal note, Ko enjoys keeping up with friendships
that began during his residency at Loyola. “It was an excellent place for
clinical training and forming long-lasting relationships with colleagues,” he
added.
Looking to hear from you
We are always happy to hear what is going on in
the lives of our alumni. The following two stories came to us via email. If
you would like your story to appear in future issues of our Newsletter , please
feel free contact us at:
surgnews@lumc.edu to share your life “after” Loyola.
Wellington Davis, M.D.
former Plastic Surgery Fellow, Graduated June 2006: “I'm
in a Craniofacial Fellowship at the Royal Children's Hospital in Melbourne,
Australia...Will finish in June 2007...Currently surviving the brushfires in
Victoria and the worst drought in Australia's history also enjoying gourmet food
and the sweet Australian lifestyle”
Dane Salazar, M.D.,
former Preliminary Surgery Resident, July 2005 - June 2006. Dr. Salazar
was Intern of the Year 2006: “I'm
stationed at Langley Air Force Base in Virginia and my job is (sounds fancier
than it is!) Flight Surgeon, 27th Fighter Squadron 1st Fighter Wing. …the near
future brings a deployment overseas. I had the distinct pleasure of flying
in F-16 Viper with the Virginia Air National Guard. They will be transitioning
to F-22 Raptors next year and coming down to Langley to join us.”
Staff Corner
The MAGIS Star Program was
established at Loyola in February, 2001. The Latin word
MAGIS, literally translated as "more," reflects one of the
distinguishing characteristics of our Jesuit institution -
the desire to do more. This program was instituted so
that members of management and/or the customers that we
serve can recognize employees that they observed
demonstrating MAGIS behaviors in their daily work
efforts. Since the implementation of this program, almost
all of our staff has been rewarded with MAGIS stars and
many have received multiple MAGIS ribbons. Employees who
collect a Star with five ribbons, have earned a Galaxy
which allows them to redeem a prize of their choosing and
they are honored at a luncheon each quarter.
Congratulations go out to the following recent Department
of Surgery MAGIS Galaxy Winners – Gail Baron (Senior
Secretary; General Surgery), Mary Martinez (Senior
Secretary; Pediatrics), Cathy Monahan (Senior Secretary;
Intra-abdominal Transplant), Colleen Tarasiewicz
(Administrative Secretary; Plastic and Reconstructive
Surgery) and Irene Zaura (Administrative Secretary;
General Surgery). All five of these employees were
honored at the MAGIS Luncheon on October 23rd.
This past October, Loyola held its Annual Pumpkin Decorating Contest. Once
again, the Department sponsored a staff entry and as in years past – the
department’s entry was one of the winners! Congratulations go out to Gail Baron
(Senior Secretary; General Surgery), Mary Martinez (Senior Secretary;
Pediatrics), Jill McHugh (Administrative Secretary; Vascular Surgery), April
Medrano (Senior Secretary; General Surgery & Trauma, Critical Care and Burns),
Nancy Mullikin (Billing Coordinator), Cathy Palumbo (Senior Secretary; Plastic
and Reconstructive Surgery), Marie Pantone (Senior Secretary; Office of
Education) and Barb Reichardt (Senior Secretary; Trauma, Critical Care and
Burns) for all their efforts in creating the Department of Surgery pumpkin
submission which took 2nd place in the contest! As 2nd Place Winners, they
won a $40 gift certificate for pizza which they shared with the staff.
In November 2006, Mary Martinez, Senior
Secretary in Pediatric Surgery, was nominated and chosen to become a MAGIS Touch
Facilitator. While all of the Surgery Staff were more than qualified to serve
as a MAGIS Facilitator, Mary stood out as someone more than deserving of this
role. Not only has Mary herself been a recipient of three MAGIS Galaxy Awards,
she is one of the first people the staff turns to in the Department to boost
morale. She’s one of the staff who always pulls together the group to
participate in the pumpkin contest....coordinates a potluck luncheon.....helps
decorate the bulletin board monthly.....gets a team together each year to walk
to raise money for Breast Cancer.....the list goes on and on. She has also
been awarded the Department of Surgery # 1 Award on three separate occasions.
Mary is currently undergoing training and will serve as a MAGIS facilitator
throughout 2007 and 2008. We are very proud of Mary and know she will be a
shining reflection on the Department of Surgery in this special role.
University Ministry asked departments throughout Loyola to put together a
Thanksgiving Basket for the less fortunate. Gail Baron, Senior Secretary in the
Division of General Surgery, generously volunteered her time and energy to
coordinate this effort on behalf of the Department of Surgery. She asked staff
members for donations and she was able to purchase not one, but two gift baskets
filled with non-perishable food items along with gift certificates for turkeys
to provide two families within the community with food for the Thanksgiving
holiday.
Each month, at the Department of Surgery Support Staff Meeting, a member of the
staff is chosen for the # 1 Award. This award is a peer-determined award
assigned by the person who held the award last. The award originated as a way
to recognize a member of our staff each month for going above and beyond. The
very first recipient of the award in January 2001, was Pam Ignarski; LAN
Administrator for the Department of Surgery. It was given to her by Surgery
Administration, because, in Sheila Fiala’s words, “… Pam is deserving of this
award…for the assistance she gives to each of the staff, faculty, and residents
on a daily basis.”
This crystal piece, in the shape of the number one has been passed to just about
every employee over the years since its inception. Below is the list of
employees who received the award during 2006.
January – April Medrano; Senior Secretary, General Surgery
February – Kathy McMahon; Senior Secretary; Plastic and Reconstructive Surgery
March – Kimberly Echert; Education Coordinator
April – Marie Pantone; Senior Secretary, Office of Education
May – Angelica Quezada; Senior Secretary, Administrative Office
June – Angela Harris; Clerkship Coordinator, Office of Education
July – Jackie Greer; Billing Coordinator
August – Nancy Mullikin; Billing Coordinator
September – Karen Pyrz; Billing Manager
October – Mary Martinez; Senior Secretary; Pediatric Surgery
November – Blanca Ramirez; Senior Secretary; Laparoscopic Surgery
December – Gail Baron; Senior Secretary; General Surgery
The Last Word
Dr. Schermer Completes the 29th Chicago
Marathon
Congratulations go out to Dr. Carol Schermer, Associate
Professor of Surgery
Division of Trauma, Surgical Critical Care, and Burns for completing the 2 9th
Chicago Marathon on Sunday, October 22, 2006. Dr. Schermer is no novice when it
comes to marathons. When questioned about her previous experience, she stated
that this was her 6th marathon, however, it was the first in thirteen
years. She previously participated in marathons in Albuquerque, New Mexico
and Long Beach, California.
Dr. Schermer said it took her “forever” to train. Although,
her opinion may differ, six months does not seem like an unreasonable length of
time to train to run a distance of 24.6 miles.
Dr. Schermer also graciously divulged her completion time,
a little less than 4 ½ hours. She added she will be competing in future
marathons and is hoping to improve her time.
Department of Surgery Well Represented at Chicago
Marathon
Dr. Schermer was not the only member of the Department of
Surgery to complete the Chicago Marathon. Vidya Shankaran, M.D. and Micah
Sinclair, M.D., both first year Residents in General Surgery, also achieved this
distinct accomplishment. Congratulations to you!!
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