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Newsletter  - Summer 2005

Welcome to the Department of Surgery Newsletter. We hope you find this information helpful.

From Where l Sit...
Richard L. Gamelli, MD, FACS

This July our department of surgery will establish a Division of Surgical Oncology.  The department’s current core of surgical oncologists will create the backbone of the division.  The surgical oncology program within the department has undergone considerable growth in its clinical activities, development of new multi-disciplinary programs and translational research initiatives. Their success has been noteworthy and I believe that they will be able to build upon these accomplishments and expand their activities with this change.

The Division of Surgical Oncology will impact on all three critical aspects of the department's mission.  Clinically, such change should provide the department with real dividends with increased ease of patients learning of our programs and faculty.  There is no clearer example of this then when one goes on the Internet and searches for a surgical oncologist.  Under our current structure our surgeons may not be easily found.  It is just as likely that they would appear with such a search under general surgery and not surgical oncology.  This divisional structure will allow greater visibility of our programs and recognition of our faculty as surgical oncologist.

Educationally, many medical students seek a residency program that provides focused training in surgical oncology as part of a broad based surgical residency. Others would select a program such as we now have in place as preparation for fellowship training in surgical oncology. Benefits will also accrue to our medical student educational program. The division has developed a creative educational curriculum for medical studies that will not only educate them in surgical oncology but provides them with life long skills at disease based management. This program will support changes educationally that are vital for preparing our students to provide patient care that is not specialty specific but addresses the patient’s broader needs with a life altering illness. The division will also be supported to further develop CME accredited training programs, conferences, and the surgical oncology lecture series.

These changes will also support our goal of growing our research programs in surgical oncology. The number of clinical trials, translational research programs and laboratory- based investigations will benefit from a focused program in surgical oncology. As a component of the Cardinal Bernadin Cancer Center and Loyola’s Oncology Institute the division will be able to strengthen its collaborations with other oncologist on campus.  The division will in addition support Loyola’s plan to become a NCI funded cancer center. 

Drs. Aranha, Gabram, Shoup and Yao have worked aggressively to expand our program and divisional status for this program is a sign of their success.  With continued growth in the areas of endocrine, colorectal, oral and maxillofacial, and plastic and reconstructive surgery further enhancements in our overall oncology based programs and ability to meet patient needs will come about with this expansion of our department.

Clinical Spotlight

Loyola Department of Surgery hosts the
Illinois Surgical Society

By: Dr. Steven DeJong 

The Loyola University Medical Center Department of Surgery hosted the Illinois Surgical Society on May 1-2, 2005. The program began with the annual Dinner-Dance held on Sunday evening, May 1, at the Oak Brook Hills Resort in Oak Brook, Illinois.  The reception and dinner was filled with lively conversation as many spent the evening renewing friendships with surgical colleagues and their spouses from the Chicago metropolitan area and all across the state of Illinois.  As one of the highlights of the evening, Dr. Jack Gibbs and Dr. Morris Kugler, the past and present historians of the society, presented a video of the history of the Illinois Surgical Society produced from the archives of the organization.  Many society members from the past and present were featured and the audience enjoyed themselves throughout the evening.  

Monday morning, May 2, the members of the Illinois Surgical Society traveled to Loyola for the Clinic Day program. A light breakfast was served in the Stritch School of Medicine to begin the day for the 50 surgeons in attendance.  The “Wet Clinic” portion of the program was held in the operating rooms in the Russo Pavilion of Loyola University. Participants were invited to view the operative procedures listed below which were performed by the surgical faculty of Loyola University Medical Center. 

Laparoscopic Gastric Banding – Dr. Vafa Shayani/ Dr. Sharfi Sarker
Right Hepatic resection – Dr. John Brems
Video Thoracoscopy with Lung resection/biopsy – Dr. Wicki Vigneswaren
Radical Cystectomy with Ieal Conduit reconstruction – Dr. Robert Flanigan
Aortic Arch Aneurysm repair – Dr. Jeffery Schwartz
Giant Splenectomy – Dr. Margo Shoup
Laparoscopic-assisted Vaginal Hysterectomy – Dr. Michael Zinaman
Resection of Retroperitoneal Sarcoma – Dr. Gerard Aranha
Femoral-Popliteal bypass – Dr. Peter Kalman
Laparoscopic Left Adrenalectomy – Dr. Steven De Jong

This experience was extremely popular and provided many examples of the variety of innovative procedures performed at Loyola. The participants were then given a tour of Loyola Medical Center and the many new buildings added to the campus over the last 5-10 years. The stops included the new Loyola Out-Patient Center, the Cardinal Bernadin Cancer Center, the Health and Fitness Center and the Stritch School of Medicine to name a few. 

The afternoon scientific session began in Tobin Hall of the Stritch School of Medicine with Dr. Richard Gamelli, Chairman of the Department of Surgery, welcoming the society and introducing Dr. Anthony Barbato, President and CEO of the Loyola University Health System. Dr. Barbato shared some of his thoughts on the current state of health care and elaborated on new developments at Loyola. Dr. Gamelli presented the history of the Loyola Department of Surgery and concluded his remarks by announcing plans to add a new surgical pavilion to the medical center.  This facility will add 12 new operating rooms to the campus along with a new Heart and Vascular Center and construction is set to begin in the fall of 2005. The rest of the program showcased many of the outstanding clinical and scientific research programs which were presented by the faculty of the Department of Surgery. The final highlight of the program was the invited guest lecture by Dr. L.D. Britt who spoke on the need for surgical specialists to maintain control and continuity of care in the Intensive Care Unit. Feedback on the entire day was extremely positive and Loyola will host the Illinois Surgical Society next in 6 years.

Resident Corner

Keeley Traveling Fellowship
By: Dr. Kimberly Brown

For the past 6 years, I’ve watched chief residents travel to faraway places, visiting some of the biggest names and places in surgery as part of the Keeley traveling fellowship, hoping that one day it would be my turn. This year – my chief year – I was fortunate enough to be awarded this unique opportunity to travel abroad and learn how things are done in the centers whose papers I’ve read for years.

I matched into a surgical oncology fellowship at Fox Chase Cancer Center in October, and shortly thereafter I began networking through Loyola as well as Fox Chase, to choose the best places for me to visit. I found the University of Pisa, in Pisa, Italy, and a Professor there named Dr. Hugo Boggi, who is good friends with one of the attendings at Fox Chase. He is an accomplished pancreatic surgeon in a tertiary referral center for pancreatic surgery and transplant. I also made arrangements to visit Hospital Paul Brousse, just outside of Paris, where the world-renowned Professor Rene Adam heads the Centre Hepato-Biliare. My husband was fortunate enough to be able to take 2 weeks off of work and join me on this European adventure.

We left Chicago Saturday April 23rd, flying through Manchester, England to arrive in Pisa Sunday afternoon. We picked up our rental car and headed for Viareggio, a sea town just north of Pisa, where we stayed for the first week. Cisanello Hospital, on the outskirts of Pisa, is a beautiful hospital campus with a whole building devoted to general, transplant, and vascular surgery. In this building are wards, ICU’s, operating rooms, and an entire radiology suite including a surgeon-ultrasonographer and a surgeon-endoscopist. The nephrologists, endocrinologists and hepatologists also have their offices and patients there, so that all of the patients are cared for by a team of medical and surgical specialists skilled in the treatment of all aspects of hepatobiliary, pancreatic, and renal diseases. I learned a great deal about the very different system of training surgeons that Italy has developed. I was able to scrub and watch many procedures, including the technique of retroperitoneal pancreas transplant, which was developed by the team at Pisa. I spoke with several professors engaged in research pertaining to the pancreas, and visited their very impressive surgical skills lab.

On the side, my husband and I found time to drive around the Tuscany region, visiting several small towns and enjoying the fantastic Italian cuisine. After our week in Pisa, we traveled to Venice for the weekend, then caught an overnight train to Paris. The Centre Hepato-Biliare just outside of Paris functions as a well-oiled machine under the command of Professor Rene Adam. I attended several multi-disciplinary conferences where every new patient is presented to the team of faculty from all aspects of patient care – hepatologists, oncologists, surgeons, radiologists, and pathologists. I attended ICU rounds with an attending boarded in both hepatology and ICU care. I scrubbed or watched many procedures including a liver transplant, partial hepatectomy, repeat hepatectomy, cryoablation, RFA, and a TIPS. I discussed research ideas with some of the faculty, including Professor Adam, including the effects of pre-op chemotherapy on liver regeneration after resection and the use of cryo versus RFA in non-resectable, non-transplantable hepatocellular carcinoma.

The Keeley fellowship was an amazing learning experience for me, from watching different surgical techniques to learning about different systems of resident training, to experiencing different cultures. I’ve made professional contacts and personal friendships that I hope will continue throughout my career. Even since returning, I met up with several members of the Pisa team at the Pancreas Club meeting in Chicago. I would recommend every surgical resident apply for the Keeley traveling fellowship, as it is a truly once-in-a-lifetime opportunity.

Reflections About Leaving Loyola
By: Dr. Sean Barnett

As I look back at the last five years of my life, I compare it to a marathon.  When I first started my internship, I lost track of the marathon part and started sprinting.  I quickly ran out of breath.  It was hard making the transition from medical student to doctor.  Patients were now MY responsibility.  I was the person responsible for getting them to the OR, through their hospital course and safely discharging them.  All the notes, forms, meds, labs, pages, blood draws, dressing changes, line insertions, and TPN orders were solely my jurisdiction.  I needed to collect the films, organize them and present each patient coherently to the attending with a logical plan during attending rounds.   

Internship was “on the job” training.  The training part as an intern required that I pushed my book knowledge to the back of my head and started with the practical.  It meant learning how to apply what I had learned in theory and implement it in a dynamic, sometimes inefficient and vexing hospital environment.  It meant learning how to organize and prioritize.  Internship is akin to boot camp.  It’s meant to be difficult and stressful.  It exposed my foundation of personal and professional strengths and weaknesses.  Loyola provided the material to rebuild my weaknesses and augment my strengths.  

The following three years are a blur.  Where does the time go?  The early part of this period was spent learning who needed an operation and how to carry it out.  The latter part of this period was spent becoming more efficient and adept at those operations and adding in the more difficult decision of who WON ‘T benefit from an operation?  It is also a time of transition from worker bee to queen (or king) bee. 

Chief resident year is the best year.  The cases I had wanted to perform so badly for the last three years were now mine.  It has been a year to spread my surgical wings with the benefit of a safety net.  Job interviews and practice selection were exciting.  Deepening my knowledge has made the practice of general surgery more rewarding.  The finish line is now within sight.   

I am indebted to all of my attendings who took the time to share their personal and academic expertise for the benefit of my growth as a general surgeon.  I have been given a wonderful foundation upon which to build a surgical career.  

Congratulations to the graduates June 2005…..
By: Dr. Sheryl Gabram

This year we say goodbye to six graduating categorical general surgery chief residents.  For various reasons, this class was unique in that two started as 1st year residents in July 2000 (Dr. Sean Barnett from Loyola Stritch School of Medicine and Dr. Olga Ivanov from Medical College of Toledo), one (Dr. Kim Brown spent two years as an NIH trauma training grant recipient with her main emphasis in the lab focusing on the effects of cholestasis and sepsis on hepatocyte apoptosis and regeneration), and three joined the program as 3rd and 4th year residents (Drs. Ata Mazaheri, Kara Kane Criswell, and Vinod Winston).  Due to their combined efforts, it was an outstanding academic year.  Dr. Kim Brown, the educational administrative chief resident, instituted the first internet based educational program with case studies, reading assignments and multiple choice questions available to residents on a weekly basis prior to the resident educational conference.  Dr. Sean Barnett, the administrative chief resident responsible for schedules and keeping the peace in the residency, kept the schedule running smoothly even with the new demands of the 80 hour work week and made sure all was well in the ranks.

I share an except from the welcome and fare well dinner on June 17th when over 200 members of the Department, residents and guests (including parents and spouses of the graduates) joined us for an evening of recognition for all of our residents but in particular to the graduating chief residents in general surgery. 

For all of the graduates this year, I leave you with 3 final thoughts: 

First, you are about to embark on a major transformation in your surgical career. Andy Grove former CEO of Intel, in his book ONLY THE PARANOID SURVIVE (a book I highly recommend to surgeons), calls such a major transformation in business “a strategic inflection point”—when the fundamentals of a business (or for you, your surgical career) are about to change drastically.  That change can mean an opportunity to rise to a new level.  Keep the fire in the belly and the passion for surgery as you start this new phase of your careers and remember that at times it will be lonely –especially when you drive away from the home ship of Loyola for the last time.  How many surgeons in the audience remember the day they left their residency?  I distinctly remember driving out of Washington DC leaving my residency for a fellowship in Hartford Connecticut and wondering where was the ticker tape parade--and saying to myself, OK, I am finally leaving everyone, goodbye—after all of those hours of work, 22,540  for this class to be exact, it suddenly ends and off you go.

Second, the world of surgery is a small circle.  Be cautious as you become a member of the surgical community whether it is in an academic or private practice setting.  You never know who you will run into years later in you career—which reminds me of a story.  Many of you have read about or personally know Dr. Grace Rozycki, distinguished trauma surgeon and known for her work in the FAST ultrasound exam.  What you probably don’t know is that, Grace and I were one year apart in training and I remember to this day confronting her in the stairwell at the Washington Hospital Center telling her to quit stealing my cases (she was a fellow and I was a chief resident at the time).  Now almost twenty years later we have formed a professional friendship, (and despite my outburst in that stairwell) she graciously agreed to be on a panel for me at the American College of Surgeons last Fall discussing academic careers in surgery—so try not to  burn any bridges that many of us probably did early on in our careers.

Third, as a leader in your surgical circle, make it meaningful.  Form the bonds of friendship with your surgical and non-surgical colleagues and try and understand where your patients are coming from.  For me this only took place in mid career and if I had to do it over again I would make it happen earlier.  It was through forming those bonds of friendship here with faculty and residents alike, as well as volunteering with the Y-Me organization when I had the opportunity to see the disease that I was treating every day through my patient’s eyes, that has really made an impact on my life as a practicing surgeon.  As surgeons we are taught to be decisively strong and maintain that professional barrier but I actually think that I am a better surgeon for occasionally crossing that barrier, forming those friendships and seeing life from a different perspective.

I end with a Chinese proverb:  If you want happiness for an hour, take a nap (and many of our chief residents did that on more than one occasion as we saw in the slide presentation tonight). If you want happiness for a day, go fishing (and they have done that too thanks to Dr. Harford). If you want happiness for a year, inherit a fortune but if you want happiness for a lifetime, help somebody. 
Thanks for all the some bodies you helped us care for as our partners over the past 5 to 7 years. Please rise for a standing ovation as we acknowledge all of the graduates tonight.

Congratulations to:

Dr. Sean Barnett as he joins former Loyola Graduates Drs Loren, Conway and Rao in private practice at Northwest Community Hospital in Arlington Heights and   Alexian Brothers Hospital in Elk Grove Village.
 

Dr. Kimberly Brown as she starts a 2 year surgical oncology fellowship at Fox Chase Cancer Center in Philadelphia.
 

Dr. Kara Criswell as she starts her 3 year plastic surgery fellowship at the University of Illinois in Chicago.
 

Dr. Olga Ivanov as she starts her 1 year fellowship in Breast Oncology at Northwestern University in Chicago.
 

Dr. Ata Mazaheri as he joins the research team at the University of Southern California studying Foregut and Thoracic Surgery in a two year research and clinical fellowship.
 

Dr. Vinod Winston as he starts his one year colorectal fellowship at the University of Louisville in Kentucky.

From the Bench

Good luck to Joanna Goral, Ph.D.  Dr. Goral completed her PhD training in the Department of Cell Biology, Neurobiology, and Anatomy and received her diploma at the graduation ceremony at the Loyola University Lake Shore Campus on May 19, 2005.  Dr Her dissertation research, performed in the laboratory of Dr Elizabeth Kovacs, was the entitled “Acute ethanol exposure inhibits Toll-like Receptor mediated inflammatory response in murine macrophages.”  On June 1, 2005, Dr Goral left Loyola to begin working as an Assistant Professor of Anatomy at Midwestern University School of Osteopathic Medicine, Downers Grove, IL. 

Eric D. Boehmer, MD/PhD student in the Department of Cell Biology, Neurobiology, and Anatomy completed the PhD portion of his training in the Dr. Elizabeth Kovacs’s laboratory.  Eric studied the effects of age on ability of murine macrophages to respond to inflammatory stimuli.  In July 2005 Eric will be returning to SSOM for the completion of his final two years of medical school. 

Congratulations to Daniel J. Fitzgerald.  Dan successfully defended his masters thesis on June 10, 2005 on a project designed to determine the mechanisms by which acute ethanol exposure impairs the early inflammatory response after dermal injury.  His work was conducted in the laboratory of Dr Elizabeth Kovacs through the Program in Cell and Molecular Biochemistry. 

The 10th Annual Meeting of the Alcohol and Immunology Research Interest Group (AIRIG) will be held on Friday November 18, 2005 in the Department of Surgery at Loyola University Medical Center in Maywood, IL.  This will be the third such meeting organized by Dr Elizabeth Kovacs and the second held at the Medical Center.  The focus of the 2005 meeting will be “Alcohol and Inflammatory and Immune Responses.”  This year, the organizers elected to limit invited speakers to junior scientists and those new to the field of alcohol and immunology.  Additionally there will be short presentations, which will be selected from abstract submissions.  There will also be a poster session and ample time for discussion.  A National Institutes of Health R13 meetings grant was submitted by Dr Kovacs to cover a portion of costs of hosting the meeting.  Sponsors of the meeting include the Loyola’s Department of Surgery and the Alcohol Research Program (ARP).  For additional information about the ARP, visit our web site www.meddean.luc.edu/arp, and for additional information about the AIRIG meeting contact Dr. Kovacs or send an email to ARP@lumc.edu

Congratulations to Katherine A. Radek, a graduate student from the Program in Biochemistry, who completed the final defense of her doctoral dissertation on May 26, 2005.  Dr. Radek performed her thesis research in the Burn and Shock Trauma Institute in the laboratory of Dr. Luisa DiPietro, where she investigated how ethanol consumption affects the healing wound.  Kathy's studies showed that even a single dose of ethanol, if taken just prior to injury, substantially slows down the healing process.  In particular, Dr. Radek discovered that the growth of capillaries into the wound is significantly slowed by ethanol consumption.  Her findings may explain why trauma patients who have consumed ethanol are at greater risk for wound healing problems.  Now that she has completed her doctoral work, Dr. Radek will be moving to California, where she will take a position as a post-doctoral research fellow at the University of California at San Diego. 

Dr. Traci Wilgus, a post-doctoral fellow in the Burn and Shock Trauma Institute, is the 2005 winner of the prestigious 3M Young Investigator Fellowship.  The 3M Fellowship is awarded by the Wound Healing Foundation, an organization with the mission of improving the quality of wound care worldwide through the funding of research and education. The highly competitive fellowship will provide a $15,000 unrestricted grant to support Dr. Wilgus' research efforts.  Dr. Wilgus plans to study how particular growth factors influence scar formation by modulating fibroblast function.  Her work may eventually suggest therapeutic measures to reduce scar formation in patients with traumatic or surgical injuries.  

 

PUBLICATIONS and APPOINTMENTS

Gerard Aranha, M.D.
Top Doctor, Chicago Metroplitan Area - 2004 – Castle Connolly
Distinguished Physician Award – Indian American Medical Association – 2004
President – Chicago Surgical Society – May, 2005 

Shoup M, Aranha GV  “Non-Standard Pancreatic Resections for Unusual Lesions”.  Am J  Surg 2005; 189:223-228 

Brown K, Domin C, Aranha GV, Shoup M “Increased preoperative platelet count is associated with decreased survival following resection for Adenocarcinoma of the pancreas”.  Am J Surg 2005; 180:278-282

 John Brems, M.D.
America’s Top Doctors for Cancer – 2005 – Castle Connolly

Kimberly Davis, M.D.
Program Committee – Western Trauma Association
Subcommittee Chairperson – Education and Registry – Chicago Committee on Trauma

Davis KA,  Eckert MJ, Reed RL, Esposito TJ, Santaniello JM, Poulakidas S and Luchette FA “Ventilator-associated Pneumonia in the Injured Patient:  Do you trust your gram stain?”  J Trauma, 58(3), 462-467, 2005.

Steven DeJong, M.D.
President – Midwest Surgical Association
Editorial Board – American Journal of Surgery

Thomas J. Esposito, M.D.
Medical Director – Rural EMS and Trauma Technical Advisory Center, Bozeman, Montana

AAAST Liaison – American Brain Trauma Foundation

Co-author – “Future of Trauma Surgery” – Journal of Trauma

Richard L. Gamelli, M.D.
President – American Burn Association

Gosain A and Gamelli, RL: The Role of the Gastrointestinal Tract in Burn Sepsis.  J Burn Care Rehabil 2005 Jan-Feb; 26(1) 7-12.

Gosain A and Gamelli, RL: A Primer in Cytokines.  J Burn Care Rehabil 2005 Jan-Feb; 26(1) 85-91.

Brewster LP and Gamelli RL: Improving Clinical Outcomes in Trauma-Related Hemorrage: Cleaning up a Bloody Mess. Issues in Hemostatis Management 2005 Jan; 1(3).

Gamelli RL
, ABA Board of Trustees, et al:  Disaster Management and the ABA Plan.  J of Burn Care & Rehabil 2005 Mar-Apr: 26(2) 102-6.

Endorf FW, Supple KG and Gamelli RL: The Evolving Characteristics and Care of Necrotizing Soft-Tissue Infections. BURNS 2005 May 31(3) 269-273.

Criswell KK and Gamelli RL: Establishing Transfusion Needs in Burn Patients:  One Institution’s Experience in Treating the Severely Burned.  Am J Surg. 2005 Mar; 189 (3):324-6.

Li X, Rana SN, Kovacs EJ, Gamelli RL,,Chaudry IH and Choudry MA:  Corticosterone suppresses Mesenteric lymph node T cell by inhibiting p-38/ERK pathway and promotes bacterial translocation following alcohol and burn injury.  Am J Physiol Regul Integr Comp Physiol. 2005 Feb 17;

Kavanaugh MJ, Clark C, Goto M, Kovacs EJ, Gamelli RL, Sayeed MM and Choudry MA:  Effect of Acute Alcohol Ingestion prior to Burn Injury on Intestinal Bacterial Growth and Barrier Function.  BURNS. 2005 May; 31(3):290-6.

Wang K, Brems JJ, Gamelli RL, Ding J:  Reversibility of caspase activation and its role during glycochenodeoxycholate-induced hepatocyte apoptosis.  J Biol Chem. 2005 Mar 14.

Davis KA, Luchette F, Santaniello J, Eckert M, Reed RL, Gamelli RL, Poulakidas S, and Esposito T: Ventilator-associated Pneumonia in Injured Patients:  Do you trust your Gram stain?  J Trauma. 2005  Mar; 58(3):462-6.

Howard J. Greisler, M.D.

President – International Society for Applied Cardiovascular Surgery
Chairman – VACO Surgery Merit Review Subcommittee for Surgery
Associate Editor – Cardiovascular Pathology

Brey E, Uriel S, Greisler HP,  Patrick C, McIntire L: Therapeutic neovascularization:  contributions from bioengineering.  Tissue Eng. 2005 Mar-Apr; 11 (3-4):567-84.

Fred Luchette, M.D.
Chair – Membership Advisory Committee – Central Surgical Association
Chair – Membership Committee – ACS COT
Secretary – Eastern Association for the Surgery of Trauma Foundation

Davis KA,  Eckert MJ, Reed RL, Esposito TJ, Santaniello JM, Poulakidas S and Luchette FA “Ventilator-associated Pneumonia in the Injured Patient:  Do you trust your gram stain?”  J Trauma, 58(3), 462-467, 2005.

 

Last Reviewed: May 8, 2006

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