Richard Cooper, MD: Publications:  (2010 – present)

Dr. Cooper Main Page

• Chiang CWK, Gajdos ZKZ, Kom JM, Kuruvilla FH, Butler JL, Hackett R, Guiducci C, Nugyen T, Wilks R, Forrester T, Chaiman CA, Henderson KD, Marchand LL, Henderson BE, Palmert MR, McKenzie CA, Lyon HN, Cooper RS, Zhu X, Hirschhorn JN.  Rapid assessment of genetic ancestry in populations of unknown origin by genome-wide genotyping of pooled samples. PLoS Genetics 2010:6(3): e 1000866 doi: 10.1371
• Kang KS, Chiang CWK, Palmer CD, Tayo BO, Lettre G, Butler JL, Hackett R, Guiducci C, Nguyen TT, Berzins I, Feng T, Ardlie K, Luke A, Adeyemo AA, Rotimi R, Wilks R, Forrester T, McKenzie C, Lyon HN, Cooper RS, Hirschhorn JN. Genome wide association of anthropometric traits in African and African-derived populations. Hum Mol Genetics. 2010;19:2725-38
• Kaufman JS, Cooper RS. Use of racial and ethnic identity in medical evaluations and treatments. I. Whitmarsh and D. S. Jones, Eds, What’s the Use of Race? Modern Governance and the Biology of Race, MIT Press, Cambridge.MA, 2010, pp 187-206.   
• Tong L, Yang J, Cooper RS. Efficient calculation of p-value and power for quadratic form statistics in multi-locus genetic association testing.  Ann Hum Genetics 2010;74:275-285.
• R. Gupta, K. Ejebe, J. Butler, G. Lettre, H. Lyon, C. Guiducci, R. Wilks, F. Bennett, T. Forrester, B. Tayo,  K. Musunuru , J. Hirschhorn, S. Kathiresan, R. S. Cooper, C. A. McKenzie.  Association of common DNA sequence variants at thirty-three genetic loci with blood lipids in individuals of African ancestry from Jamaica. Hum Mol Genetics. 2010;128:557-561.
• Qin H, Morris N, Kang S, Li M, Tayo B, Lyon HN, Hirschhorn J, Cooper RS, Zhu X. Interrogating local population structure in genome-wide association studies. Bioinformatics. 2010;26:2961-2968.  
• Mujahid MS, Diez-Roux AV, Cooper RS, Shea S, Williams DR. Neighborhood stressors and race/ethnic differences in hypertension prevalence (The Multi-Ethnic Study of Atherosclerosis).  Am J Hypertens. 2010 Sep 16.
• Boyne MS, Bennett NR, Cooper RS, Royal-Thomas Y, Bennett NL, Luke A, Wilks F, Forrester TE. Sex differences in adiponectin levels and body fat distribution. Longitudinal observations in Afro-Jamaicans.  Diabetes Res Clin Pract 2010;90;e33-36
• Hassanein MT, Lyon HN, Henderson B, Le Marchand L, Stram DO, Waters K, Zhu X, Cooper RS, Tayo B, Akylbekova M, Taylor H, McKenzie C. Fine-mapping of the association with obesity at the FTO locus in African-derived populations. Hum Mol Genetic 2010;19:2907-16
• Kramer H, Cao G, Dugas L, Luke A, Cooper R, Durazo-Arvzu R. Increasing BMI and waist circumference and prevalence of obesity among adults with type 2 diabetes: the National Health and Nutrition Examination Surveys. J Diabetes Complications. 2010;24:368-74. 
• Ferguson T, Younger N, Tulloch-Reid M, Wright ML, Forrester T, Cooper RS, Van den Broeck J, Wilks R. Progression from pre-hypertension to hypertension in a Jamaican cohort: Incident hypertension and its predictors. West Ind J Med. 2010;59:486-493.
• Gil-Guillen VF, Orozco-Beltran DL, Redon J, Pita Fernandez S, Navarro-Perez J, Pallares V, Valls F, Fluixa C, Fernandez A, Martin-Moreno JM, Pascual de la Torre M, Trillo JL, Durazo-Arvizu R, Cooper R, Hermenegildo M, Rosado L. Rationale and methods of the Cardiometabolic Valencian Study (ESCARVAL-Risk) for validation of risk scales in Mediterranean patients with hypertension, diabetes or dyslipidemia.  BMC Public Health 2010;10:717      
• Ferguson TS, Younger N, Tulloch-Reid MK, Forrester TE, Cooper RS, Van den Broek J, Wilks RJ. Prevalence of metabolic syndrome in Jamaican adults and its relationship to income and economic level. West Indian Med J 2010;59:265-73.     
• Flegal KM, Graubard KI, Williams DF, Cooper RS. Reverse causation and bias in observational studies and weight loss and mortality: Unresolved issues and research directions. Am J Epidemiol 2011;173:1-9. 
• Franco M, Cooper RS, Bilal U, Fuster V. Challenges and opportunities in cardiovascular prevention.  Am J Med. 2011;124:95-102
• Simino J, Shi G, Kume R, Schwander K, Province MA, Gu CG, Kardia S, Chakravarti A, Ehret G, Olshen RA, Turner ST, Jaquish C, Paltoo D, Cooper RS, Weder A, Curb D,  Boerwinkle E, Hunt SC, Rao DC. Five blood pressure loci identified by an updated genome-wide linkage scan: Meta-analysis of the Family Blood Pressure Program. Am J Hypertension. 2011;24:347-354.  
• Fox ER, et al; Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource (CARe) Study. Human Mol Genetic 2011;20:2273-2284. 
• Wang W, Zhu X, Cooper RS, Ewens WJ, Li C, Li M. Adjustment for local ancestry in genetic association analysis of admixed populations. Bioinformatics 2011;27:670-677.   
• Chiang, CWK, Gajdos ZKZ, Korn JM, Butler JL, Hackett R, Guiducci C, Nguyen TT, Wilks R, Forrester T, Henderson KD, Marchand LL,  Henderson BE, Haiman CA, Cooper RS, Lyon HN, Zhu X, McKenzie CA, Palmert MR, Hirschhorn JN. The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA. Hum Genetics  2011; 
• Redon J, Olsen M, Cooper RS, Zurriaga O, Martinez M, Laurent F, Chiftkova R, Coca A, Mancia G. Variation in stroke mortality and secular trends in 39 countries from Europe and Central Asia: Implications for blood pressure control. Eur Heart J. 2011;32:1424-1431
• Luke A, Dugas L, Durazo-Arvizu R, Cao G, Cooper RS. Activity patterns in the US population and their relationship to cardiovascular risk factors: NHANES 2003-2006. BMC Public Health. 2011; 25;11:387
• Tayo B, Luke A, McKenzie C, Durazo-Arvizu R, Adeyemo A, Forrester T, Kramer H, Cooper RS. Sodium, potassium and blood pressure in population surveys in Nigeria, Jamaica and the US. J Hum Hypertens. 2011;
• Tayo BO, Thiel M, Tong L, Qin H, Khtrov G, zhang W, Zhu X, Pereira A, Cooper RS, Bottinger EP. Genetic background of patients from a university medical center in Manhattan: Implications for personalized medicine.  PLoS One . 2011 May 4;6(5):e19166
• Zhu X, Young H, Fox E, Keating B, Franceschini N, Kang S, Tayo B, Adeyemo A, Sun Y, Rotter J, Cooper R, Redline S, Chakravarti A, Levy D. Combined admixture mapping and association analysis identifies a novel blood pressure genetic locus on 5p13: Contributions from the CARe consortium. Hum Mol Genetics. 2011;20:2285-2295
• Chakravarti et al, The International Collaboration for Blood Pressure Genome-Wide Association Studies. Common polymorphisms impacting blood pressure and cardiovascular disease in diverse populations highlight novel biological pathways. Nature. 2011;479:103-109.
• Franco M, Cooper R, Bilal U, Fuster V. Control of CHD risk factors and evidence-based therapies; Joint efforts for coronary heart disease prevention in Spain. Revista Espanola Cardiologia 2011;64:962-964.
• Bhatia G, et al. Genome-wide comparison of African-origin populations from CARe and other cohorts reveals signals of selection. Am J Hum Genetics. 211;83:368-281
• N'diaye A et al. HYPERLINK "http://preview.ncbi.nlm.nih.gov/pubmed/21998595" Identification, replication, and fine-mapping of loci associated with adult height in individuals of African ancestry. PLoS Genet. 2011 Oct;7(10):e1002298
• International Consortium for Blood Pressure Genome-Wide Association Studies. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/21909115" Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Hum Mol Genet. 2011 Jun 1;20(11):2273-84.
• Luke A, Bovet P, Forrester TE, Lambert EV, Plange-Rhule J, Schoeller DA, Dugas L, Durazo-Arvizu RA, Shoham D, Cooper RS, Brage S, Ekelund U, Steyn N. Protocol for the Modeling the Epidemiologic Transition Study: a longitudinal observational study of energy balance and change in body weight, diabetes and cardiovascular disease risk. BMC Public Health 2011:11:901
• Orzoco-Beltran D, Redon J, Durazo-Arvizu R, Pita S, Cooper RS, Paar ES, Gil V. Is there a predictive profile for clinical inertia in hypertensive patients? An observational, cross-sectional, multi-centre study. Drugs Aging 2011;28:981-992.
• Tong L, Tayo B, Yang J, Cooper RS. Comparison of SNP-based and gene-based association studies in detecting rare variants using unrelated individuals. BMC Proc. 2011 Nov 29;5 Suppl 9:S41
• Shoham DA, L Tong, PJ Lamberson, AH Auchincloss, J Zhang, JS Kaufman, RS Cooper, A Luke. An actor-based social network model of adolescent body size, screen time, and playing sports. PLoS One 2012;7(6):e39795
• Reder N, Tayo B, Cooper R. Adrenergic alpha-1 receptor pathway is associated with hypertension among Nigerians in a pathway-focused analysis. PLoS One. 2012;7(5):e37145
• Shetty PB, Tang H, Tayo BO, Morrison AC, Hanis CL, Rao DC, Young JH, Fox ER, Boerwinkle E, Cooper RS, Risch NJ, Zhu X; the Candidate Gene Association Resource (CARe) Consortium. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/22914544" Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping. J Hypertens. 2012
• Orozco-Beltran D, Cooper RS, Gil-Guillen V, Bertomeu-Martinez V, Pita-Fernandez S, Durazo-Arvizu R, Carratala-Munuera C, Cea-Calvo L, Bertomeu-Gonzalez V, Seoane-Pillado T, Rosado LE. HYPERLINK "http://www.ncbi.nlm.nih.gov/pubmed/22727798" Trends in mortality from myocardial infarction. A comparative study between Spain and the United States: 1990-2006. Rev Esp Cardiol. 2012
• Tayo B, Salako T, Cooper RS, Bottinger E, Kramer H, McKenzie C, Oguniyi A, Gottesman O. Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians. Int Urol Nephrology 2012