Otolaryngology Head & Neck Surgery

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Research

Residents and faculty in the Department of Otolaryngology and in collaboration with adjunct scientists are engaged in all aspects of research, including basic laboratory investigations, human clinical trials and clinical outcomes studies. Current basic research topics include mechanisms of wound healing, factors impacting nerve function after facial nerve and recurrent laryngeal nerve crush injury, genomics of head and neck cancer, mechanisms of cancer invasion and metastasis, tumor angiogenesis and studies of the immunosuppressive properties of head and neck cancer.

Outcomes studies are focused on the efficacy of middle ear perfusion for sudden deafness and incapacitating vertigo, facial function and hearing preservation in skull base surgery, resource utilization and functional outcomes in head and neck cancer, cost-effective treatment of sinusitis and minimally invasive and image guided surgery.

Each year, the Department of Otolaryngology holds the Annual Peter J. Girgis Resident Research Competition.  Originally started in 1991, this program honors excellency in resident research projects, as judged by visiting internationally recognized leaders in the field.  Resident research is further encouraged with the four-month research rotation, incorporated into the PGY-3 year.

The faculty in the Department of Otolaryngology along with Loyola clinicians in Radiation and Medical Oncology and Dental Medicine participate in multi-institution trials coordinated by the Southwest Oncology Group, Radiation Therapy Oncology Group, National Cancer Institute and the American College of Surgeons Oncology Group as well as multiple industry sponsored trials.

Learn about our current Clinical Trials.

Recent Publications/Presentations

"Chondroblastoma of the Sphenoid Sinus." Burgin, SJ; Porter, RG; Mehrota, S; Welch, KC. In Press.

"Temporal Bone Osteoradionecrosis After Surgery and Radiotherapy for Malignant Parotid Tumors.” Leonetti, JP; Marzo, SJ; Zender, CA; Porter, RG; Melian, E. Otol Neurotol. 2010 Jun;31(4):656-9.

"Recurrent Post-Tympanostomy Tube Otorrhea Secondary to Aerobic Spore-Forming Bacilli: A Case Report and Brief Literature Review.” Jaber, J; Thorpe, E; Kircher, M; Porter, RG; Leonetti, JP; Marzo, SJ. Ear, Nose, & Throat Journal. In Press.

"Comparison of Extratemporal and Intratemporal Facial Nerve Injury Models.” Sharma N; Cunningham, K; Porter, RG; Marzo, SJ; Jones, KJ; Foecking, EM. Laryngoscope. 2009 Dec;119(12):2324-30.

"Effects of Electrical Stimulation and Gonadal Steroids on Rat Facial Nerve Regenerative Properties” Sharma, N; Coughlin, L; Porter, RG; Tanzer, L; Wurster, RD; Marzo, SJ; Jones, KJ; Foecking, EM. Restor Neurol Neurosci. 2009;27(6):633-44

"Effect of Adipose Graft Usage on Postoperative Headache Following Retrosigmoid Craniotomy” Porter, RG; Leonetti, JP; Ksiazek, J; Anderson, DE. Otol Neurotol. 2009 Aug;30(5):635-9.

Dr. John Leonetti- Surgical Management of Facial Neuromas: Lessons Learned

Dr. Sam Marzo- Facial Nerve Schwannoma

Dr. James Jaber- A 25-Year Analysis of Veterans Treated for Tonsillar Squamous Cell Carcinoma

Dr. James Jaber- Cervical Spine Causes for Referred Otalgia

Dr. James Jaber- Evolving Treatment Strategies in Thin Cutaneous Head and Neck Melanoma: One Institution's Experience

Dr. Matthew Kircher- Neuroradiologic Assessment of Pulsaile Tinnitus

Electrical Stimulation Facilitates Rat Facial Nerve Recovery

Late Facial Nerve Decompression Surgery: Analysis of 20 Cases and a Brief Literature Review

Facial Nerve Injury and Repair: Development of Treatment Strategies for Clinical Application

Analysis of End-User Perceived Benefit with the Bone-Anchored Cochlear Stimulator (BAHA) Using the Abbreviated Profile of Hearing Aid Benefit (APHAB) in a Clinical Setting

Grants

The first grant is an Intramural Funding through Loyola's Research Funding Committee in combination with the Neurscience Institute. This grant is a translational grant to do research in collaboration with the Otolaryngology Department (Eileen Foecking, Sam Marzo).

PI: Sam Marzo, MD
Project Title: Recurrent Laryngeal Nerve Injury: Use of Androgens as a Pre-Clinical Method of Treatment
Project Type: Translation
Funding Source: Loyola University Research Funding Committee
Funding Period: Jan 2009- Jan 2011
Funding Total: $40,000

PI: Carol Bier-Laning, MD
Project Title: Loss of Heterozygosity Initiated by Apoptotic DNA Cleavage in Head and Neck Cancer
Project Type: Basic Science
Funding Source: Triological Society Career Development Award
Funding Period: 8/1/2008-12/31/2009
Funding Total: $40,000

P.I.: Dr. Kathyrn J. Jones
Title: Facial Nerve Injury and Repair: Development of Treatment Strategies for Clinical Application
Project Type: Translational
Funding from RFC: $30,000
Funding from Neuroscience Institute: $25,000
Funding time: 1 year

The second grant is a pilot study through the VA.

P.I.: Dr. Kathyrn J. Jones
Title: Development of an Intratemporal Compression Model of the Rat Facial Nerve
Funding Total: $50,000
Funding time: 1 year

 

Last Reviewed: Jul. 7, 2010

Department: (708) 216-1676
Appointments: (708) 216-8563

Learn about our current Clinical Trials.


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