REACTIONS TO INJURY


  

The liver possesses a remarkable regenerative capacity therefore the process of repair by regeneration proceeds to complete restitutio ad integrum.If however the damage has affected the reticular framework,the repair will occur by scar formation (fibrosis) which may lead to rearrangement of the blood circulation and to cirrhosis.

The reaction to injury proceeds as is follows:

  • 1. DAMAGE (necrosis)
    • cellular changes
    • tissue changes
  • 2. INFLAMMATORY REACTION
  • 3. REPAIR
    • by regeneration (restitutio ad integrum)
    • by scarring (fibrosis)













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